Results 61 to 70 of about 603,752 (273)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Assessing seventh-grade students' computational thinking skills through problem-based learning: Focus on integer addition and subtraction

Journal of Honai Math
Computational thinking is a crucial skill that facilitates problem-solving for students. Recognizing its importance, the PISA 2021 framework incorporates computational thinking to enhance problem-solving and mathematical reasoning abilities. However, the
Hapizah Hapizah, Anadia Muli Mariela, Budi Mulyono   +2 more
doaj   +1 more source

Potential for Meaning Making in Mathematics Textbooks

Designs for Learning, 2019
A Multimodal Analysis of Subtraction in Swedish Year 1   Textbooks are a common teaching tool widely used in children’s mathematical education. Comparative studies of textbooks have focused on different aspects, such as content, mathematical symbols and ...
Malin Norberg
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Development of a Subtraction Processing Technology for Assistance in the Comparative Interpretation of Mammograms

Diagnostics
A comparative interpretation of mammograms has become increasingly important, and it is crucial to develop subtraction processing and registration methods for mammograms.
Chiharu Kai, Satoshi Kondo, Tsunehiro Otsuka, Akifumi Yoshida, Ikumi Sato, Hitoshi Futamura, Naoki Kodama, Satoshi Kasai   +7 more
doaj   +1 more source

Number processing and arithmetic skills in children with cochlear implants

Frontiers in Psychology, 2014
Though previous findings report that hearing impaired children exhibit impaired language and arithmetic skills, our current understanding of how hearing and the associated language impairments may influence the development of arithmetic skills is still ...
Silvia ePixner, Martin eLeyrer, Korbinian eMoeller   +2 more
doaj   +1 more source

Continuous-variable measurement-device-independent quantum key distribution with photon subtraction

, 2018
It has been found that non-Gaussian operations can be applied to increase and distill entanglement between Gaussian entangled states. We show the successful use of the non-Gaussian operation, in particular, photon subtraction operation, on the continuous-
Bai, Dong-Yun, Bao, Wan-Su, Huang, Peng, Ma, Hong-Xin, Wang, Shi-Yu, Zeng, Gui-Hua   +5 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Achieving arithmetic learning in honeybees and examining how individuals learn

Communicative & Integrative Biology, 2019
In recent years honeybees have demonstrated intriguing numerical capacities, leading to the recent discovery of their ability to perform simple arithmetic by learning to add or subtract ‘one’ using symbolic representations of operators.
Scarlett R. Howard, Aurore Avarguès-Weber, Jair E. Garcia, Andrew D. Greentree, Adrian G. Dyer   +4 more
doaj   +1 more source

Antenna subtraction for gluon scattering at NNLO

, 2010
We use the antenna subtraction method to isolate the double real radiation infrared singularities present in gluonic scattering amplitudes at next-to-next-to-leading order.
A Daleo, A Daleo, A Freitas De, A Gehrmann-De Ridder, A Gehrmann-De Ridder, A Gehrmann-De Ridder, A Gehrmann-De Ridder, A Gehrmann-De Ridder, A Gehrmann-De Ridder, A Gehrmann-De Ridder, A Gehrmann-De Ridder, A Gehrmann-De Ridder, A Gehrmann-De Ridder, A Gehrmann-De Ridder, A Gehrmann-De Ridder, C Anastasiou, C Anastasiou, C Anastasiou, C Anastasiou, C Anastasiou, C Anastasiou, C Anastasiou, CF Berger, D Kosower, DA Kosower, DA Kosower, DA Kosower, DA Kosower, DA Kosower, DA Kosower, E. W. Nigel Glover, EWN Glover, EWN Glover, EWN Glover, FA Berends, FA Berends, G Altarelli, G Dissertori, G Dissertori, G Dissertori, G Heinrich, G Heinrich, G Heinrich, G Ossola, G Somogyi, G Somogyi, G Somogyi, G Somogyi, G Somogyi, JM Campbell, JM Campbell, Joao Pires, K Hasegawa, K Melnikov, M Czakon, M Grazzini, ML Mangano, ML Mangano, P Bolzoni, R Frederix, R Frederix, R Kleiss, S Bethke, S Catani, S Catani, S Catani, S Catani, S Catani, S Catani, S Catani, S Catani, S Catani, S Frixione, S Frixione, S Frixione, S Weinzierl, S Weinzierl, S Weinzierl, S Weinzierl, S Weinzierl, S Weinzierl, S Weinzierl, SD Badger, SD Ellis, SD Ellis, SD Ellis, T Binoth, T Binoth, T Binoth, T Binoth, T Gehrmann, T Gleisberg, TG Birthwright, TG Birthwright, U Aglietti, V Duca Del, WB Kilgore, WT Giele, WT Giele, WT Giele, Z Bern, Z Bern, Z Bern, Z Bern, Z Bern, Z Bern, Z Bern, Z Bern, Z Nagy   +108 more
core   +1 more source