Results 121 to 130 of about 560,921 (309)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
, 2008 . Key longstanding difficulties associated with subtyping can be avoided by using type unification instead of subtyping on function argument types. In particular, the types of method specialisations need only be unifiable subtypes of the method’s default
C. Barry Jay
core
Unifying typing and subtyping [PDF]
, 2017 In recent years dependent types have become a hot topic in programming language research. A key reason why dependent types are interesting is that they allow unifying types and terms, which enables both additional expressiveness
Yanpeng Yang +3 more
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Tropical Medicine and Infectious DiseaseInfluenza sentinel surveillance in Libya was formally established in 2022 by the Libyan National Center for Disease Control (NCDC). Between 2022 and 2024, a total of 1864 nasopharyngeal specimens were collected from patients presenting with influenza ...
Mahmud Azbida +12 more
doaj +1 more source
An Aptamer-Based Probe for Molecular Subtyping of Breast Cancer
Theranostics, 2018 Molecular subtyping of breast cancer is of considerable interest owing to its potential for personalized therapy and prognosis. However, current methodologies cannot be used for precise subtyping, thereby posing a challenge in clinical practice.
Mei Liu +8 more
semanticscholar +1 more source
, 1996 Constrained type systems are a natural generalization of Hindley/Milner type inference to languages with subtyping. This paper develops several subtyping relations on constrained types.
Scott Smith, Valery Trifonov
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Staphylococcus aureus entrance into the dairy chain: Tracking S. aureus from dairy cow to cheese
Frontiers in Microbiology, 2016 Staphylococcus aureus is one of the most important contagious mastitis pathogens in dairy cattle. Due to its zoonotic potential, control of S. aureus is not only of great economic importance in the dairy industry but also a significant public health ...
Judith Kümmel +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source