Results 201 to 210 of about 83,566 (244)

EFFECTIVE PROTECTION AGAINST INFLUENZA AFTER VACCINATION WITH SUBUNIT VACCINE

Medical Journal of Australia, 1978
Immunization with an influenza subunit vaccine given in one dose about 1 month to 2 months before onset of an epidemic of influenza afforded from 80% to 90% protection in a double-blind clinical trial which was supported by isolation of virus and serological studies. In the vaccinated group, 20% failed to develop antibodies to the vaccine.
M L, Hammond, A A, Ferris, S, Faine, T, McAvan   +3 more
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Feline calicivirus subunit vaccine - a prototype

Antiviral Research, 1985
A vaccine was prepared from a subunit component, antigenically similar to the whole feline calicivirus (FCV) particles. Despite the limited number of animals available for this study we were able to demonstrate that the vaccine protected cats when challenged with a virulent strain of the virus while the non-vaccinates kept as controls developed ...
O O, Komolafe, O, Jarrett
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Design and production of recombinant subunit vaccines

Biotechnology and Applied Biochemistry, 2000
The development of subunit vaccines is presently the main strategy being evaluated for prevention of infectious diseases. The use of recombinant‐DNA techniques has facilitated the development of new principles for design and production of subunit vaccines.
M, Hansson, P A, Nygren, S, Ståhl
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Infectious Bursal Disease Subunit Vaccination

Avian Diseases, 2008
Infectious bursal disease virus (IBDV) is the causative agent of infectious bursal disease, a nosologic entity with global economic importance in poultry. The viral protein 2 (VP2) is recognized as the virus' major antigenic protein. The goal of this study was to generate yeast (Pichia pastoris)-based protein expression from the VP2 gene of the Edgar ...
Pedro, Villegas, M, Hamoud, L B, Purvis, F, Perozo   +3 more
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KILLED SUBUNIT INFLUENZA VACCINE IN CHILDREN

Pediatrics, 1973
Thirty-three children ranging in age from 5 to 9 years were immunized with varying doses of bivalent A2 (Hong Kong variant) B subunit influenza vaccine. The immunization was given intramuscularly. There were no local or systemic reactions. Thirty-one of 33 children (94%) demonstrated four-fold or greater rises in antibody titer to type A antigen ...
C F, Phillips, C A, Phillips, W E, Hodgkin, B R, Forsyth, B A, Rubin, M E, Geraghty   +5 more
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Adjuvants and Subunit Vaccines

2010
1 Adjuvants 2 Subunit Vaccines 3 Acknowledgments Keywords: adjuvants and subunit vaccines; immunological phenomena-triggered by vaccine adjuvants; antigen-presenting cells (APC)-activation and expansion of antigen-specific T- and B-cell populations.; new vaccine adjuvants; adjuvants licensed for use in humans, MF59; bacterial ...
Giuseppe Del Giudice, Rino Rappuoli
openaire   +1 more source

Potency of a Scalable Nanoparticulate Subunit Vaccine

Nano Letters, 2018
Nanoparticulate vaccines can potentiate immune responses by site-specific drainage to lymph nodes (LNs). This approach may benefit from a nanoparticle engineering method with fine control over size and codelivery of antigen and adjuvant. Here, we applied the flash nanocomplexation (FNC) method to prepare nanovaccines via polyelectrolyte complexation of
Dongdong Qiao, Lixin Liu, Yi Chen, Chenbao Xue, Qiang Gao, Hai-Quan Mao, Kam W. Leong, Yongming Chen   +7 more
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Clinical Trial of a Subunit Influenza Vaccine

Scandinavian Journal of Infectious Diseases, 1981
A double-blind field trial was performed comparing a subunit influenza vaccine (A/Victoria/75 and B/Hongkong/73) with placebo. A good protection against influenza was induced by the vaccine. On the basis of serological determinations (enzyme immunoassay, EIA) the incidences of influenza A and B infections were reduced within a period from 3 weeks up to
S, Pyrhönen, J, Suni, M, Romo
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Peptide vaccination is superior to genetic vaccination using a recombineered bacteriophage λ subunit vaccine

Vaccine, 2012
Genetic immunization holds promise as a vaccination method, but has so far proven ineffective in large primate and human trials. Herein, we examined the relative merits of genetic immunization and peptide immunization using bacteriophage λ. Bacteriophage λ has proven effective in immune challenge models using both immunization methods, but there has ...
Brad S, Thomas, Sandra, Nishikawa, Kenichi, Ito, Puja, Chopra, Navneet, Sharma, David H, Evans, D Lorne J, Tyrrell, Oliver F, Bathe, Derrick E, Rancourt   +8 more
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The case for a subunit vaccine against malaria

Trends in Parasitology, 2011
New technologies and some disillusionment with subunit vaccines has led to increased interest in the development of whole parasite vaccines for malaria. Instead, the current priority should be to build on the partial success of the recombinant protein sporozoite vaccine, RTS,S.
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