Results 71 to 80 of about 3,686,701 (344)

Trends in the Management of Intracranial Vascular Malformations in the USA from 2000 to 2007

Stroke Research and Treatment, 2012
Objective. To assess prevalence, clinical characteristics, trends in treatment pattern, and outcome in patients with intracranial vascular malformations (IVMs). Methods. Nationwide inpatient sample.
Jae H. Choi, John Pile-Spellman, Jonathan Brisman   +2 more
doaj   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Age- and tactic-related paternity success in male African elephants [PDF]

, 2007
Henrik B. Rasmussen, John B. A. Okello, George Wittemyer, Hans R. Siegismund, Peter Arctander, Fritz Vollrath, Iain Douglas‐Hamilton   +6 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

24. Facial Feminization Surgery: Region-specific Importance Recognized by Artificial and Human Intelligence Gender Recognition Correlates with Patient Satisfaction

Plastic and Reconstructive Surgery, Global Open, 2023
Joshua Choe, MS, Dana Bregman, MD, Meghan Miller, BA, James P. Bradley, MD   +3 more
doaj   +1 more source

The student well-being monitor: identifying trends in higher education in The Netherlands

Cogent Education
The well-being of students in higher education has received increasing attention, particularly in the aftermath of the Covid-19 pandemic. This study investigates trends in student well-being at a multi-campus university of applied sciences in the ...
Elisabeth F. Klinkenberg, Rutger F. Kappe   +1 more
doaj   +1 more source

The Prediction of Psychotherapy Success by Outcome Expectations in Inpatient Psychotherapy [PDF]

, 2011
Martin Grosse Holtforth, Tobias Krieger, Katharina Bochsler, Birgit Mauler   +3 more
openalex   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source