Results 131 to 140 of about 1,125,152 (340)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Succession in Private Firms as an Entrepreneurial Process – A Review and Suggestions of New Research avenues [PDF]

In considering firm succession as the acts of both entrepreneurial exit and entry, this paper adds to work that seeks to integrate entrepreneurship and family business research. We provide a comprehensive literature review of succession research over the
Bau, Massimo, Hellerstedt, Karin, Nordqvist, Mattias, Wennberg, Karl   +3 more
core  

Geoacoustic Velocity of Basement and Tertiary Successions of the Okgye and Bukpyeong Coast, East Sea [PDF]

, 2007
Woo-Hun Ryang, Yi-Kyun Kwon, Jae-Hwa Jin, Hyuntae Kim, Chi-Won Lee   +4 more
openalex   +1 more source

Microbial community succession during crude oil-degrading bacterial enrichment cultivation and construction of a degrading consortium [PDF]

, 2022
Tianfei Yu, Xiaodong Liu, Jiamin Ai, Jiamin Wang, Yidan Guo, Xinhui Liu, Xiaolong He, Zhenshan Deng, Yingying Jiang   +8 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

SUCCESSION ON YOUNG AND MEDIUM AGE FALLOWS OFTHE FOREST-STEPPE ZONE OFWESTERN SIBERIA IN THE NOVOSIBIRSK REGION [PDF]

, 2018
S.V. Solovev, G.F. Miller, Natalia Bezborodova, D.A. Filimonova   +3 more
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

South Wales [PDF]

, 2011
Carboniferous rocks in this region occur in a broadly east-west trending syncline, the core of which includes the South Wales and Pembrokeshire coalfields (Fig. 5.1).
Barclay, W.J., Cleal, C.J., Davies, J.R., Jones, N.S., Waters, C.N., Waters, R.A.   +5 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source