Results 241 to 250 of about 218,507 (292)

Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment

Rare Metals, EarlyView.
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang, Jiatong Lin, Yi Peng, Zehua Wu, Yingying Liu, Wei Duan, Qiaolin Wei, Jia‐Wei Shen, Jiang‐Xing Chen, Yong Guo   +9 more
wiley   +1 more source

Novel Wide‐Spectrum Virucidal Lipid Nanoparticles

Small, EarlyView.
POSTAN is a novel broad‐spectrum antiviral nanoparticle that combines safety with potent virucidal activity. Composed of biocompatible lipids, it mimics heparan sulfate proteoglycans and lipid rafts exploited by viruses, thereby dismantling viral envelopes and blocking replication.
Yugo Araújo Martins, Louise Bondeelle, Arnaud Charles‐Antoine Zwygart, Thais Melquiades de Lima, Juliano de Paula Souza, Han Kang Tee, Fernando Chahud, Eurico de Arruda Neto, Francesco Stellacci, Renata Fonseca Vianna Lopez, Caroline Tapparel   +10 more
wiley   +1 more source

Immune and metabolic signatures characterise constipation-driven endophenotypes in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Figliomeni A, Winter S, Abonnel M, Kenna J, Lodge S, Whiley L, Bernal A, Coudert JD, Noonan J, Kaskow B, Anderton R.   +10 more
europepmc   +1 more source

Clinicopathologic features of succinate dehydrogenase deficiencient renal cell carcinoma.

, 2020
Qing Zhu, Xia Wu, Yuan‐Li Huang, Mingyang Tang, Ligao Wu   +4 more
openalex   +1 more source

Electrospun Polybutylene Succinate Coatings for Sustainable Cardboard Packaging: Structure‐Property Relationships [PDF]

Allison Vercasson, Cristina Prieto, Sébastien Gaucel, Nathalie Gontard, Valérie Guillard, Hélène Angellier‐Coussy, José M. Lagarón   +6 more
openalex   +1 more source

Activatable smart contrast agents for photoacoustic imaging

Smart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh, Jihye Lee, Suyoung Park, Juyoung Yoon, Won Jong Kim, Chulhong Kim   +5 more
wiley   +1 more source

Quantitative Nuclear Magnetic Resonance Spectroscopic Method Development and Validation of Sumatriptan Succinate in Pharmaceutical Tablet Dosage form

, 2018
Mangarao Nakka, Srinivas Nakka, V Hsu, M Ferrari, The, G Plosker, D Mctavish, M Bousser, H Allens, Richard, M Hoerlein, G Mcmonigle, D Franz, V Rizzo, V Pinciroli, F Malz, H Jancke, B Tanja, S Curd, S Ravi, Y Darwis, N Khan, L Singh, S Nanda, R, K Buridi, Raghubabu, Rajesh Kumar, N, Sunil Kumar, S, Susanta Kumar, P, B Kalyanaramu, K Raghubabu, B Amruta, C Upendra, W Shrikant, B Santhakumari, Shah C R*, B Suhagia, N Shah, Shah R R   +42 more
openalex   +1 more source

An Integrated Method to Evaluate the Treatment Efficacy and Immunogenicity of B‐Cell Acute Lymphoblastic Leukemia Therapeutic Enzyme Formulations

Small Methods, EarlyView.
This work presents an integrated set of methods to evaluate the efficacy of asparaginase formulations against B‐cell Acute Lymphoblastic Leukemia (ALL) in mice, including the establishment of an ALL murine model, an amino acid depletion study using high‐performance liquid chromatography (HPLC), and comprehensive assessment of antibody production ...
Julien Santelli, Annie Y. Heble, Connor Endsley, Adam Woodward, Nazia Hafeez, Naomi Winick, Jacques Lux   +6 more
wiley   +1 more source

Presurgical Succinate MetAstatic Risk Tool (P-SMART) in Paragangliomas. [PDF]

Endocr Pathol
Rapizzi E, Zanatta L, Santi A, Staderini F, Galeotti N, Ercolino T, Amore F, Sparano C, Maggi M, Canu L.   +9 more
europepmc   +1 more source

Novel Bio‐Based Polyurethane Elastomers Customizable for Orthopedic Devices: Toughness, Rapid Degradability, and Safety

SusMat, EarlyView.
ABSTRACT Given the increasing global demand for sustainable materials and growing concerns over the depletion of petrochemical resources, we report the synthesis of an amorphous bio‐derived polyester diol, and this diol was polymerized with various isocyanates and butanediol, yielding a novel series of bio‐based polyurethane elastomers (BPUEs). Notably,
Chenxin Xu, Yushu Tian, Hengheng Zhao, Jiadong Wang, Qingjun Wang, Xiang Lin, Jun Liu, Zhao Wang, Xuan Qin, Liqun Zhang   +9 more
wiley   +1 more source