Results 251 to 260 of about 193,960 (302)
Regulation of succinate dehydrogenase and role of succinate in cancer
Seminars in Cell and Developmental Biology, 2020 Succinate dehydrogenase (SDH) has been classically considered a mitochondrial enzyme with the unique property to participate in both the citric acid cycle and the electron transport chain. However, in recent years, several studies have highlighted the role of the SDH substrate, i.e.
Elisa Dalla Pozza +2 more
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Succinate in the cancer–immune cycle
Cancer Letters, 2017 Succinate is an important intermediate of the tricarboxylic acid (TCA) cycle. In mitochondria, it plays a crucial role in generating adenosine triphosphate.
Shuai Jiang
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Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels [PDF]
Journal of Biological Chemistry, 2016 peer reviewedMetabolic reprogramming is emerging as a hallmark of the innate immune response, and the dynamic control of metabolites such as succinate serves to facilitate the execution of inflammatory responses in macrophages and other immune cells ...
Martina Wallace +2 more
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Desvenlafaxine succinate monohydrate
Acta Crystallographica Section C Crystal Structure Communications, 2008The title compound {systematic name: [2-(1-hydroxycyclohexyl)-2-(4-hydroxyphenyl)ethyl]dimethylammonium 3-carboxypropanoate monohydrate}, C(16)H(26)NO(2)(+) x C(4)H(5)O(4)(-) x H(2)O, is a succinate salt of O-desmethylvenlafaxine (desvenlafaxine). The present structure is one of four reported polymorphs of this salt, which is a new antidepressant drug.
Nalivela, Venu +3 more
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Thyroxine and succinate oxidation
Archives of Biochemistry and Biophysics, 1956Abstract 1. 1. Thyroxine preserves the activity of succinate-cytochrome c reductase activity in preparations from rat heart homogenate, but does not increase the original activity. 2. 2. The preservation appears to be a chemical rather than physical effect. 3. 3.
B J, KRIPKE, A T, BEVER
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The application of succine in sports
Voprosy kurortologii, fizioterapii i lechebnoi fizicheskoi kul'tury, 2015The development of energy deficiency in the course of physical exercises that eventually leads to serious derangement of the energy metabolism is an important component of the deterioration of physical and intellectual working capacity. The most promising approach to the correction of impaired physical and intellectual working capacity associated with ...
S V, Okovityi, S V, Rad'ko
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2-Aminopyridinium–succinate–succinic acid (2/1/1)
Acta Crystallographica Section C Crystal Structure Communications, 2002In the title compound, 2C(5)H(7)N(2)(+).C(4)H(4)O(4)(2-).C(4)H(6)O(4), cyclic eight-membered hydrogen-bonded rings exist involving 2-aminopyridinium and succinate ions. The succinic acid and succinate moieties lie on inversion centres. Succinic acid molecules and succinate ions are linked into zigzag chains by O-H.O hydrogen bonds, with O.O distances ...
Buyukungor, O, Odabaşoğlu, Mustafa
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Succinate metabolism of hemoflagellates
Experimental Parasitology, 1956Abstract Extracts of the hemoflagellates, Trypanosoma cruzi and Crithidia fasciculata catalyze the reduction of ferricytochrome c in the presence of succinate. The reduction is inhibited by malonate. The rate of cytochrome reduction is approximately six times as rapid as is the oxidation of ferrocytochrome c.
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Succination of proteins in diabetes
Free Radical Research, 2010Cysteine is arguably the most reactive amino acid in protein. A wide range of cysteine derivatives is formed in vivo, resulting from oxidation, nitrosation, alkylation and acylation reactions. This review describes succination of proteins, an irreversible chemical modification of cysteine by the Krebs cycle intermediate, fumarate, yielding S-(2 ...
Norma, Frizzell +2 more
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