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Alkylation Reactions of Hydantoins and Succinimides
Journal of Pharmaceutical Sciences, 1973Five anticonvulsant agents, namely, diphenylhydantoin, mephenytoin, ethotoin, ethosuximide, and phensuximide, and a number of other hydantoins were investigated in their reactions with p- and m-nitrobenzyl bromides in the presence of sodium carbonate. The structures of the alkylation derivatives and other products formed in the reactions were studied ...
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