Results 1 to 10 of about 43,444 (345)

Evaluation of Site-Specific Radioiodination of Anti-EGFR-Targeted DARPin E01 Using (4-Hydroxyphenyl)ethyl Maleimide. [PDF]

Int J Mol Sci
Larkina M, Yanovich G, Hasnowo LA, Varvashenya R, Eskova D, Sharychev I, Prach A, Plotnikov E, Zelchan R, Schulga A, Konovalova E, Ziganshin RH, Belousov M, Tolmachev V, Deyev SM.   +14 more
europepmc   +2 more sources

Mechanochemical Diastereoselective Substrate-Directed Synthesis of Pyrrole-Isoxazolidines via 1,3-Dipolar Cycloaddition of Maleimides with Nitrones. [PDF]

J Org Chem
de Jesus IS, Lédo AFDC, Ferrer A, A Bueno M, Cunha S.   +4 more
europepmc   +2 more sources

Domino Synthesis of Coumarins via Phosphine-Mediated Formal <i>Oxa</i>-[4 + 2] Cycloaddition: Discovering a Missing Recyclization of Maleimides with Salicylaldehydes. [PDF]

J Org Chem
Barretto FA, de Castro PP, de Oliveira KT, Cunha S.   +3 more
europepmc   +3 more sources

Maleimide-Functionalized Liposomes: Prolonged Retention and Enhanced Efficacy of Doxorubicin in Breast Cancer with Low Systemic Toxicity

Molecules, 2022
Cell surface thiols can be targeted by thiol-reactive groups of various materials such as peptides, nanoparticles, and polymers. Here, we used the maleimide group, which can rapidly and covalently conjugate with thiol groups, to prepare surface-modified ...
Chuane Tang, Dan Yin, Tianya Liu, Rui Gou, Jiao Fu, Qi Tang, Yao Wang, Liang Zou, Hanmei Li   +8 more
doaj   +1 more source

Stability of Maleimide-PEG and Mono-Sulfone-PEG Conjugation to a Novel Engineered Cysteine in the Human Hemoglobin Alpha Subunit

Frontiers in Chemistry, 2021
In order to use a Hemoglobin Based Oxygen Carrier as an oxygen therapeutic or blood substitute, it is necessary to increase the size of the hemoglobin molecule to prevent rapid renal clearance.
Chris E. Cooper, Matthew Bird, XiaoBo Sheng, Ji-Won Choi, Gary G.A. Silkstone, Michelle Simons, Natalie Syrett, Riccardo Piano, Luca Ronda, Luca Ronda, Stefano Bettati, Stefano Bettati, Gianluca Paredi, Andrea Mozzarelli, Andrea Mozzarelli, Brandon J. Reeder   +15 more
doaj   +1 more source

Catalyst-Free Green Synthesis of Dithiocarbamate and Rhodanine Derivatives via C─S and C─N Bond Formation Using N-Substituted Maleimides. [PDF]

Chem Asian J
Satani P, Soliya S, Dutta S, Naveen T.
europepmc   +3 more sources

Evaluation of Substituted N-Aryl Maleimide and Acrylamides for Bioconjugation

AppliedChem, 2023
Novel SF5-bearing maleimide and acrylamide derivatives were synthesised as potential [18F]radio-prosthetic groups for radiolabelling peptides and proteins.
Hugh G. Hiscocks, Giancarlo Pascali, Alison T. Ung   +2 more
doaj   +1 more source

Pyrrolobenzodiazepine Antibody-Drug Conjugates Designed for Stable Thiol Conjugation

Antibodies, 2017
Thiosuccinimide-linked antibody-drug conjugates (ADCs) are susceptible to drug loss over time due to a retro-Michael reaction, which can be prevented by selecting stable conjugation positions or hydrolysis of the thiosuccinimide.
R. James Christie, Arnaud C. Tiberghien, Qun Du, Binyam Bezabeh, Ryan Fleming, Amanda Shannon, Shenlan Mao, Shannon Breen, Jing Zhang, Haihong Zhong, Jay Harper, Herren Wu, Philip W. Howard, Changshou Gao   +13 more
doaj   +1 more source

A BODIPY-Based Probe Enables Fluorogenicity via Thiol-Dependent Modulation of Fluorophore Aggregation

Molecules, 2022
Given the popular usage of BODIPY fluorophores in biological research, their propensity to aggregate in aqueous solution and impact their spectroscopic properties arguably warrants more attention. The probe under study herein serves as a case in point. A
Tak Ian Chio, Akiva J. Grimaldi, Thomas I. Radford, Susan L. Bane   +3 more
doaj   +1 more source

Effect of different kinds of maleimide resins on properties of nitrile rubber

Hecheng xiangjiao gongye, 2021
Curing characteristics，physical and mechanical properties，and thermal oxidative pro-perty of nitrile rubber （NBR） vulcanized by N-cyclohexylmaleimide，2，2′-bis[4-（4-maleimide phenoxy）phenyl]propane （BMP-BMI） and N，N′-（4，4′-diphenylmethane） bismaleimide ...
LI Bo1; DU Dong-hua2; HUANG Xi-dai1; ZHAO Hong-guo1; WU Zhou-quan3; XU Dian-hong1; GONG Zi-qing1; ZHOU Lei1; XIE Song-bai4; WU Yu1; HU Hai-hua1
doaj   +1 more source