Results 31 to 40 of about 39,650 (248)
Maleimido-Functionalized NOTA Derivatives as Bifunctional Chelators for Site-Specific Radiolabeling
Molecules, 2011 Two basic and simple synthetic routes for mono- and bis-maleimide bearing 1,4,7-triazacyclononane-N,N’,N’’-triacetic acid (NOTA) chelators as new bifunctional chelators are described. The syntheses are characterized by their simplicity and short reaction
Jörg Steinbach +3 more
doaj +1 more source
Maleimide-modification reaction parametersa.
, 2016 Maleimide-modification reaction parametersa.
Christopher G. Rowe (3181443) +7 more
core +1 more source
On-Demand Detachment of Maleimide Derivatives on Cysteine to Facilitate (Semi)Synthesis of Challenging Proteins [PDF]
, 2020 The maleimide group is a widely used reagent for bio-conjugation of peptides, proteins and oligonucleotides employing Michael addition and Diels-Alder cycloaddition reactions.
Guy, Mann +5 more
core +2 more sources
Drugs and Drug CandidatesBackground: Idiopathic pulmonary fibrosis (IPF) is a chronic, disabling disorder of unknown etiology, poor prognosis, and limited therapeutic options. Previously, 3′5-dimaleamylbenzoic acid (3′5-DMBA) was shown to exert resolving effects in IPF, offering
Karina González-García +6 more
doaj +1 more source
Functionalization of photochromic dithienylmaleimides† [PDF]
RSC Advances, 2015 Photochromic dithienylmaleimides are well known molecular switches, but for applications the suitable functionalization of the photochromic scaffold is required.
D. Wutz +3 more
doaj +1 more source
Photoinduced Transformations with Diverse Maleimide Scaffolds
MoleculesMaleimides serve as crucial components in various synthetic processes and are of significant interest to researchers in bioorganic chemistry and biotechnology.
Jayachandran Parthiban +2 more
doaj +1 more source
Automated three-component synthesis of a library of γ-lactams
Beilstein Journal of Organic Chemistry, 2012 A three-component method for the synthesis of γ-lactams from commercially available maleimides, aldehydes, and amines was adapted to parallel library synthesis. Improvements to the chemistry over previous efforts include the optimization of the method to
Erik Fenster +3 more
doaj +1 more source
, 2016 In situ binding of thiol-reactive prodrugs to the cysteine-34 position of circulating albumin is a new approach in drug delivery. Therefore, five maleimide-bearing derivatives of the anticancer drug camptothecin (CPT) were developed as albumin-binding ...
Felix Kratz (1926430) +1 more
core +1 more source
Green Chemistry Letters and Reviews, 2019 This paper describes the design and implementation of a minimally hazardous, environmentally friendly, and energy efficient sequential reaction sequence within a sophomore level Organic Chemistry lab course to efficiently synthesize N-phenylmaleimide ...
Loyd D. Bastin +5 more
doaj +1 more source
A pyrene maleimide with a flexible linker for sampling of longer inter-thiol distances by excimer formation. [PDF]
PLoS ONE, 2011 Pyrene-containing compounds are commonly used in a number of fluorescence-based applications because they can form excited-state dimers (excimers) by stacking interaction between excited-state and ground-state monomers.
Satomi Niwayama +4 more
doaj +1 more source