Results 51 to 60 of about 43,444 (345)

Synergistic Integration of Liquid Crystalline Ordering and Dynamic Networks for Ultrarobust Bismaleimide Vitrimers

open access: yesAdvanced Functional Materials, EarlyView.
A liquid‐crystalline bismaleimide vitrimer integrates local mesogenic organization with exchange‐active ester connectivity, achieving a glass‐transition temperature near 300°C while remaining reprocessable. Stress‐relaxation analysis and temperature‐dependent remolding reveal how segmental mobility, network rearrangement, and structural integrity ...
Woohyeon Kwon   +3 more
wiley   +1 more source

Development of applicable thiol-linked antibody–drug conjugates with improved stability and therapeutic index

open access: yesDrug Delivery, 2022
Maleimides are typically applicable for coupling with reactive thiol moieties of antibodies in antibody–drug conjugates (ADCs) via the thiol-Michael click chemistry.
Yanming Wang   +6 more
doaj   +1 more source

Chemo‐ and Diastereoselectivities in the Electrochemical Reduction of Maleimides [PDF]

open access: yesChemSusChem, 2015
AbstractThe electrochemical cathodic reduction of cyclic imides (maleimides) to succinimides can be achieved chemoselectively in the presence of alkene, alkyne, and benzyl groups. The efficiency of the system was demonstrated by using a 3D electrode in a continuous flow reactor.
Rix, K   +3 more
openaire   +3 more sources

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari   +10 more
wiley   +1 more source

Synthesis of maleimide-modified gelatin: Avoiding the peculiar case of maleimide polymerization

open access: yesInternational Journal of Biological Macromolecules
Gelatin, a widely used protein biopolymer in the food industry, also holds great potential for biomedical applications because of its unique characteristics. To fully harness its potential, modification is often required, such as the introduction of maleimide groups, which enable conjugation with thiols via very fast thiol-maleimide Michael addition ...
Raeymaekers, Ruben   +3 more
openaire   +3 more sources

-Alkoxy Maleimide Derivatives as Labeling Reagents for Biomolecules [PDF]

open access: yes, 2021
An efficient procedure to access tritium-labeled maleimide derivatives in a high specific activity has been developed. N-Substituted maleimides containing the hydroxy functionality are O-methylated in a three-step synthesis route, including (1) Diels ...
Martin R. Edelmann   +3 more
core   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

open access: yesAdvanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi   +3 more
wiley   +1 more source

Maleimide Functionalized Siloxane Resins [PDF]

open access: yes, 1999
In-situ filling through hydrolysis and condensation of silicon alkoxides dissolved into polymers has been utilized to generate nanocomposites in which the filler phase can be intimately associated with the polymer on relatively small length scales.
D. A. Loy, D. R. Wheeler, R. M. Shaltout
core   +3 more sources

Maleimide

open access: yes, 2004
Inelastic Neutron Scattering spectrum of Maleimide, C₄H₃NO₂, measured on the TFXA ...
S.F. Parker, ISIS, Rutherford Appleton Laboratory, UK
core   +1 more source

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