Results 61 to 70 of about 39,650 (248)
, 2016 Monomers allowing for the introduction of [2,5-dimethylfuran]-protected maleimides into polyamides such as peptides, peptide nucleic acids, and peptoids were prepared, as well as the corresponding oligomers.
Enrique Pedroso (61530) +4 more
core +1 more source
Maleimide-bearing nanogels as novel mucoadhesive materials for drug delivery [PDF]
, 2016 Novel maleimide-functionalised nanogels have been synthesised via the polymerisation of 2,5-dimethylfuran-protected 3-maleimidoethyl butylacrylate in the presence of presynthesised poly(N-vinylpyrrolidone) (PVP) nanogel scaffolds using surfactant-free ...
Tonglairoum, Prasopchai +3 more
core +1 more source
Advanced Science, EarlyView.A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li +9 more
wiley +1 more source
Антибиотики и Химиотерапия, 2020 Biological properties of new synthetic triindolylmethylium antibiotics of the triindolylmethane group, including compounds containing a maleimide fragment in the structure, are studied.
E. P. Mirchink +8 more
doaj
Infection and Drug Resistance, 2021 Qing Zhan,1 Yanlei Xu,1 Lingling Zhan,2 Bingjie Wang,3 Yinjuan Guo,3,4 Xiaocui Wu,3,4 Wenxiu Ai,5 Zengqiang Song,6 Fangyou Yu3,4 1Jiangxi Provincial Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang, 330006 ...
Zhan Q +8 more
doaj
Maleimide-Decorated PEGylated Mucoadhesive Liposomes for Ocular Drug Delivery
Liposomes are promising spherical vesicles for topical drug delivery to the eye. Several types of vesicles were formulated in this study, including conventional, PEGylated, and maleimide-decorated PEGylated liposomes.
Sergey K. Filippov (1296339) +4 more
core +1 more source
Quantum‐Trained AI Enables Inverse Design of Organic Frontier Orbitals at Billion‐Scale
Advanced Science, EarlyView.Quantum‐trained AI links molecular substructures to frontier‐orbital energetics and enables interpretable screening across nearly one billion GDB‐13 molecules. By combining fragment‐ and ring‐level insights with donor–acceptor energy alignment against ITIC, the framework narrows an immense chemical space to a small set of promising candidates and ...
Yeongnam Ko, Se Jin Kim, Ki Chul Kim
wiley +1 more source
Novel 1H-Pyrrole-2,5-dione (maleimide) proxies for the assessment of photic zone euxinia [PDF]
, 2015 1H-Pyrrole-2,5-diones (maleimides) and 1-alkyl-2,3,6-trimethylbenzenes (aryl isoprenoids), degradation products of tetrapyrrole pigments and carotenoids respectively, were analysed and compared with pristane/phytane (Pr/Ph) ratios to reconstruct past ...
Kliti Grice (7507532) +1 more
core +2 more sources
, 2016 The reaction of maleimide-containing compounds with 2,5-dimethylfuran gives a mixture of exo and endo isomers from which the exo cycloadduct can be easily isolated taking advantage of its stability in concentrated aqueous ammonia.
Enrique Pedroso (61530) +2 more
core +1 more source
Tuning the Diels–Alder Reaction for Bioconjugation to Maleimide Drug-Linkers [PDF]
, 2018 The thiol–maleimide linkage is widely used for antibody–drug conjugate (ADC) production; however, conjugation of maleimide–drugs could be improved by simplified procedures and reliable conjugate stability.
Christie, R James +29 more
core +1 more source