Results 31 to 40 of about 8,040 (169)

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2723-2740, August 2026.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source

The Use of Succinylcholine in Brugada Syndrome: A Case Report and Discussion of Literature

Case Reports in Anesthesiology, 2019
We describe a patient with a major depression and a newly discovered Brugada syndrome, who was successfully treated with 35 electroconvulsive therapy sessions using succinylcholine as muscle relaxant.
Marcus M. de Wolf, Nellie M. Rus, Guus H. Beljaars, Hanno L. Tan   +3 more
doaj   +1 more source

Malignant hyperthermia (literature review)

Вестник анестезиологии и реаниматологии, 2023
The objective – to summarize the current literature data on the etiology, pathogenesis, diagnosis and treatment of malignant hyperthermia.   The search and analysis of literature data on malignant hyperthermia in the medical information systems PubMed ...
R. R. Tukhvatullina, N. V. Matinyan
doaj   +1 more source

Comparison of emergence agitation between succinylcholine and rocuronium-sugammadex in adults following closed reduction of a nasal bone fracture: a prospective randomized controlled trial

BMC Anesthesiology, 2019
Background Sugammadex allows rapid recovery from rocuronium-induced neuromuscular blockade. Succinylcholine is often used for brief surgeries but is associated with myalgia, headache, histamine release, and increased lactate levels. Thus, we hypothesized
Seok-Jin Lee, Tae-Yun Sung, Choon-Kyu Cho   +2 more
doaj   +1 more source

Anesthetic consideration for patients with nemaline rod myopathy: a literature review. [PDF]

Pediatric Anesthesia and Critical Care Journal (PACCJ), 2017
emaline rod myopathy is a rare and heterogeneous condition with an incidence of approximately two per 100,000 per live birth. The disease encompasses a broad spectrum of morbidity ranging from mild symptoms to lethality in the newborn period.
NH. Tran, D. Smith
doaj   +1 more source

Error Traps in Pediatric Neuromuscular Block

Pediatric Anesthesia, Volume 36, Issue 8, Page 887-898, August 2026.
ABSTRACT Background Neuromuscular blocking agents are essential for safe pediatric anesthesia but remain a frequent source of preventable morbidity when misused, inadequately monitored, or incompletely reversed. Children, particularly neonates and infants, are especially vulnerable to residual neuromuscular block due to developmental pharmacological ...
Gabriel Soares de Sousa, Debra Faulk, Vinicius Caldeira Quintao, Niekoo Abbasian, Hans D. de Boer, Ricardo Vieira Carlos   +5 more
wiley   +1 more source

Anesthetic Consideration of Patient With Myotonic Dystrophy Type 1: A Case Report and Review of Literature

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Myotonic dystrophy type 1 (DM1) presents significant anesthetic challenges. A 46‐year‐old woman with DM1 underwent emergent exploratory laparotomy. This case highlights the importance of conservative neuromuscular blocker dosing, quantitative neuromuscular monitoring, clinically‐guided timing of sugammadex administration, careful airway ...
Yun Chin Lin, Wendy Hitt, Blake Han, Sallie Canumay, Juan Liuzzi Stamerra, Ioana Pasca, Leonard Soloniuk, Benjamin Kuo   +7 more
wiley   +1 more source

#53. A Paralyzing Consequence: Succinylcholine-Induced Hyperkalemia, a Rare but Dangerous Side Effect §

Graduate Medical Education Research Journal
Mentor: Ryan Mullane Program: Internal Medicine Type: Case Report Background: Succinylcholine is a depolarizing neuromuscular blockade agent used during general anesthesia.
Hannah Kruger, Ryan Mullane, Kathleen Borghoff   +2 more
doaj   +1 more source

EndoFLIP Guided Assessment of Pyloric Distensibility Identifies Associations With Delayed Gastric Emptying and Symptoms of Gastroparesis

Neurogastroenterology &Motility, Volume 38, Issue 7, July 2026.
Measuring pyloric distensibility at high balloon volumes using EndoFLIP differentiates normal from delayed gastric emptying, while pyloric stiffness specifically correlates with increased subjective feeling of stomach fullness. EndoFLIP could be a valuable clinical tool to phenotype the pyloric sphincter in symptomatic patients.
Subhankar Chakraborty, Adam Spandorfer, Flavio Bonilla, Kebire Gofar, Ladan Navari   +4 more
wiley   +1 more source

Association Between Inflammatory Cytokines (IL‐6 and IL‐10) and Trauma Severity: Correlations With Shock Index and ABC Score in Trauma Patients—A Prospective Observational Study

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Trauma is a leading cause of disability and mortality worldwide, with outcomes influenced by inflammatory responses. This study evaluated the association between trauma severity scores—Shock Index (SI) and Assessment of Blood Consumption (ABC) score—and systemic cytokine levels (IL‐6 and IL‐10) to assess their potential ...
Rodrigo Gonçalves de Oliveira, Marina Tiemi Shio, André Luis Lacerda Bacchi, Ana Paula Ribeiro, Rodrigo Olivio Sabbion, Patrícia Colombo‐Souza   +5 more
wiley   +1 more source