Results 111 to 120 of about 54,072 (222)

A TLR8 Variant Identified From Whole Exome Sequencing as a Sepsis‐Prone Mutation

FASEB BioAdvances, Volume 8, Issue 4, April 2026.
Whole‐exome sequencing of sepsis patients identified a recurrent high‐impact TLR8 rs3764880 variant enriched in bacterial sepsis. Single‐cell transcriptomics localized elevated TLR8 expression to non‐classical monocytes, while bulk RNA‐seq and functional assays demonstrated enhanced IFN‐β responses following TLR8 stimulation.
Fahd Alhamdan, Stefano Gianoli, Xioahui Han, Sophia Koutsogiannaki   +3 more
wiley   +1 more source

Prevalence of new‐onset diabetes following COVID‐19 infection: A systematic review and meta‐analysis

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3182-3192, April 2026.
Abstract Aim To estimate the prevalence of new‐onset diabetes in adults (≥ 18 years) following SARS‐CoV‐2 infection. Materials and Methods This meta‐analysis includes studies written in English that measured the number of adults (≥ 18 years) diagnosed with diabetes following SARS‐CoV‐2 infection.
Jordan N. Keels, Rose D. LaPlante, Christopher S. Lee, Andrew A. Dwyer   +3 more
wiley   +1 more source

First report of dengue virus among febrile malaria positive and negative patients in Nyala city, Western Sudan

Journal of Microbiology and Infectious Diseases
Background: The mosquito borne dengue fever and malaria -; are major public health concerns in tropical settings. They are highly prevalent and considered one of the main etiology of febrile illnesses in Sudan.
Smah Ishag, Abdel Rahim M El Hussein, Isam M Elkhidir, Khalid A Enan   +3 more
doaj   +1 more source

Yellow Fever Outbreak, Southern Sudan, 2003

Emerging Infectious Diseases, 2004
In May 2003, an outbreak of fatal hemorrhagic fever, caused by yellow fever virus, occurred in southern Sudan. Phylogenetic analysis showed that the virus belonged to the East African genotype, which supports the contention that yellow fever is endemic ...
Clayton O. Onyango, Antoinette A. Grobbelaar, Georgina V.F. Gibson, Rosemary C. Sang, Abdourahmane Sow, Robert Swanepoel, Felicity J. Burt   +6 more
doaj   +1 more source

Protease inhibitors targeting coronavirus and filovirus entry. [PDF]

, 2015
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet, Barnard, Dale, Carrion, Ricardo, Lu, Kai, McKerrow, James H, Nunneley, Jerritt W, Pöhlmann, Stefan, Renslo, Adam R, Simmons, Graham, Vedantham, Punitha, Zhou, Yanchen   +10 more
core   +1 more source

Vaccines at the Heart of Hepatitis Elimination: Insights From the ESCMID Study Group for Viral Hepatitis (ESGVH)

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT The global elimination of viral hepatitis by 2030 remains an ambitious goal that hinges not only on diagnostics and therapeutics but fundamentally on the strategic use and continued innovation of vaccines. The ESCMID Study Group for Viral Hepatitis (ESGVH) convened to examine the role of vaccination as the cornerstone of hepatitis prevention ...
Oana Săndulescu, Gülşen Özkaya Şahin, Susanne Gjeruldsen Dudman, Zeinab Nabil Ahmed Said, Mario U. Mondelli, on behalf of ESCMID Study Group for Viral Hepatitis (ESGVH)   +5 more
wiley   +1 more source

Occult Hepatitis B Virus in Gezira State Sudan

Sudan Journal of Medical Sciences, 2014
Background: Occult hepatitis B infection (OBI) is simply defined as serologically undetectable hepatitis B surface antigen (HBsAg-ve), despite the presence of circulating HBV DNA.Objective: The aim of this study was to determine the prevalence of occult HBV among Screened HBsAg subjects in Gezira State, Sudan.Materials and Methods: A total of 176 ...
Gasmelseed, N, Elsir, AA, Elhaj, EY, Saeed, OK, Elbalal, M   +4 more
openaire   +1 more source

Unravelling Uncertainty After Displacement: Syrian and Eritrean Women's Homemaking Processes in The Netherlands

Tijdschrift voor Economische en Sociale Geografie, Volume 117, Issue 2, Page 214-232, April 2026.
Abstract Using a ‘homemaking’ rather than an ‘integration’ lens to study people's negotiations of space in new environments, we study post‐displacement homemaking processes of Syrian and Eritrean women in the Netherlands. Fleeing from different ordeals, these women arrived during the refugee‐protection crisis of 2015 and work to (re)arrange their ...
Iris Poelen, Lothar Smith
wiley   +1 more source

Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates

Nature Communications, 2019
Current experimental monoclonal antibodies (mAbs) for Ebola virus (EBOV) post-exposure immunotherapy are ineffective against Sudan (SUDV) or Marburg virus (MARV).
Jennifer M. Brannan, Shihua He, Katie A. Howell, Laura I. Prugar, Wenjun Zhu, Hong Vu, Sergey Shulenin, Shweta Kailasan, Henna Raina, Gary Wong, Md Niaz Rahim, Logan Banadyga, Kevin Tierney, Xuelian Zhao, Yuxing Li, Frederick W. Holtsberg, John M. Dye, Xiangguo Qiu, M. Javad Aman   +18 more
doaj   +1 more source

Nosocomial Outbreak of Crimean-Congo Hemorrhagic Fever, Sudan

Emerging Infectious Diseases, 2010
To confirm the presence of Crimean-Congo hemorrhagic fever in Sudan, we tested serum of 8 patients with hemorrhagic fever in a rural hospital in 2008. Reverse transcription–PCR identified Crimean-Congo hemorrhagic fever virus. Its identification as group
Imadeldin E. Aradaib, Bobbie R. Erickson, Mubarak E. Mustafa, Marina L. Khristova, Nageeb S. Saeed, Rehab M. Elageb, Stuart T. Nichol   +6 more
doaj   +1 more source