Results 161 to 170 of about 272,522 (346)

Hypoxia‐Induced Histone Lactylation Promotes Ferroptosis in Cardiomyocytes via the Wnt/β‐Catenin Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the effects of histone lactylation on ferroptosis in hypoxia‐induced cardiomyocytes. A hypoxia model was established in AC16 cells treated with 2‐Deoxy‐D‐glucose (2‐DG, a glucose analogue), ferrostatin‐1 (Fer‐1, a selective ferroptosis inhibitor), lactate (LA), sh‐β‐catenin (shRNA of β‐catenin), or SKL2001 (an agonist ...
Xin‐Hua Zhu   +6 more
wiley   +1 more source

Heart Failure with Preserved Ejection Fraction and Sudden Death: How to Identify High Risk Patients?

open access: yesJournal of Cardiac Arrhythmias, 2020
Background: Cardiac failure with preserved ejection fraction corresponds to half of the cardiac failure cases, having a similar prognosis to patients with reduced ejection fraction.
Bruno Finkler   +7 more
doaj  

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa   +7 more
wiley   +1 more source

Cystatin C and Sudden Cardiac Death Risk in the Elderly

open access: green, 2010
Rajat Deo   +9 more
openalex   +2 more sources

Personalized Arrhythmic Risk Stratification for Sudden Cardiac Death in Ischemic, Non-ischemic, and Hypertrophic Cardiomyopathy Patients: The Two-Step, Non-invasive Risk Factors Guiding to Electrophysiology Study Approach

open access: green, 2023
Πέτρος Αρσένος   +12 more
openalex   +2 more sources

Cardiac resynchronization therapy and pulmonary artery banding in advanced heart failure infants with left ventricular dilated cardiomyopathy and left bundle branch block

open access: yesPediatric Investigation, EarlyView.
The combination of cardiac resynchronization therapy and pulmonary artery banding was associated with substantial improvement in advanced heart failure infants with left ventricular dilated cardiomyopathy and left bundle branch block. Most patients exhibited marked improvement in clinical status and ventricular function, along with a reduction in QRS ...
Min Zeng   +8 more
wiley   +1 more source

Multifrequency Multiparameter Magnetic Resonance Elastography Applied to an In Vivo Porcine Model for Assessing Portal Hypertension

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Portal hypertension, a critical complication in chronic liver disease, has long relied on invasive hepatic venous pressure gradient measurement for definitive diagnosis. This study establishes that multifrequency three‐dimensional magnetic resonance elastography (3D‐MRE) can noninvasively quantify portal pressure, with splenic stiffness and loss ...
Bai Du   +6 more
wiley   +1 more source

Sudden cardiac death in children and adolescents (excluding Sudden Infant Death Syndrome)

open access: yesAnnals of Pediatric Cardiology, 2010
Sudden death in the young is rare. About 25% of cases occur during sports. Most young people with sudden cardiac death (SCD) have underlying heart disease, with hypertrophic cardiomyopathy and coronary artery anomalies being commonest in most ...
Gajewski Kelly, Saul Philip
doaj  

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