Results 181 to 190 of about 261,378 (297)

Sudden cardiac death.

The Yale journal of biology and medicine, 1978
Over the past decade, there has been a significant decrease in the hospital mortality of patients with coronary artery disease. However, sudden cardiac death, which accounts for the majority of deaths from coronary artery disease, hasbeen little affected.
openaire   +1 more source

A novel selective stabilizer of the ryanodine receptor 2 prevents stress‐induced ventricular arrhythmias without impairing cardiac function

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Aberrant activation of type 2 ryanodine receptors (RyR2) causes lethal arrhythmias, such as catecholaminergic polymorphic ventricular tachycardia (CPVT). Developing drugs that suppress RyR2 hyperactivation may be key to novel arrhythmia treatments.
Nagomi Kurebayashi, Masami Kodama, Hana Inoue, Masato Konishi, Masami Sugihara, Takashi Murayama, Ryosuke Ishida, Koichiro Ishii, Shuichi Mori, Yukari Endo, Xi Zeng, Yukiko U. Inoue, Takayoshi Inoue, Satoru Noguchi, Hajime Nishio, Eri Nakashima, Norio Suzuki, Noriko Nakaya, Ryushi Sato, Yuya Otori, Ayuna Tsutsumi, Mirei Takahashi, Takayuki Oka, Haruo Ogawa, Kayoko Kanamitsu, Hiroyuki Kusuhara, Utako Yokoyama, Junko Kurokawa, Hiroyuki Kagechika, Takashi Sakurai   +29 more
wiley   +1 more source

Left ventricular ejection fraction and myocardial fibrosis in sudden cardiac death. [PDF]

Europace
Silvola H, Holmström L, Pakanen L, King I, Eskuri A, Tikkanen J, Perkiömäki J, Huikuri H, Junttila J.   +8 more
europepmc   +1 more source

Diltiazem N‐oxide, a novel ischaemia‐activated prodrug, prevents ischaemia‐induced ventricular fibrillation without off‐target adverse effects

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ventricular fibrillation (VF) in coronary heart disease accounts for up to 70% of sudden cardiac death. We examined whether diltiazem N‐oxide (DNO) has ischaemia‐selective antiarrhythmic activity. Experimental Approach Randomised and blinded experiments were performed in rat isolated hearts and in anaesthetised rats to ...
Louise M. Hesketh, Gabriel A. Watson, Francesca Mazzacuva, Zoe Hoare, Thomas R. Eykyn, Michael J. Curtis   +5 more
wiley   +1 more source

Sudden cardiac death in adults living with HIV: A systematic review. [PDF]

PLoS One
Pierzchalski J, Cunnigham N, Kooij K, Guillemi S, Smith R, McCandless L, Hogg R.   +6 more
europepmc   +1 more source

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

Clinical Endocrinology, EarlyView.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth, Thomas J. O'Leary, Craig L. Doig, Natalie Taylor, Jasminder Dosanjh, David R. Woods, Michael J. Stacey, Robert M. Gifford   +7 more
wiley   +1 more source

Sudden cardiac death and the role of postmortem genetic testing in unexplained cases. [PDF]

Indian Pacing Electrophysiol J
Rajan D, Skjelbred T, Hadberg Lynge T, Tfelt-Hansen J.   +3 more
europepmc   +1 more source

Advances in Electrocardiogram‐Based Non‐Invasive Blood Glucose Monitoring Technology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Blood glucose monitoring is fundamental to diabetes management, yet traditional invasive methods are limited by patient discomfort and infection risks. In recent years, electrocardiogram (ECG), a conventional tool for cardiovascular assessment, has gained attention as a prospective method for non‐invasive blood glucose monitoring.
Qi Zeng, Jiaying Ni, Ziyi Zhang, Jinghao Cai, Jingyi Lu, Jian Zhou   +5 more
wiley   +1 more source

Layer-specific proteomic analysis of human hearts in patients with sudden cardiac death. [PDF]

PLoS One
Kakimoto Y, Guan X, Ueda A, Kimura Y, Akiyama T, Tanaka M, Ikeda H, Maeda K, Isozaki S.   +8 more
europepmc   +1 more source

Air embolism secondary to suspected lymphatic tissue disruption with severe exercise‐induced pulmonary haemorrhage

Equine Veterinary Education, EarlyView.
Summary Air embolism is rare in horses and typically associated with complications following intravenous catheterisation or other medical procedures. Exercise‐induced pulmonary haemorrhage (EIPH) is common in racehorses but not usually associated with air embolism. This report describes a case of air embolism in a 4‐year‐old Thoroughbred with EIPH. The
J. Wittenberg, K. Drozdzewska, K. Landmann, A. Voß, K. Kunze, D. Rutenberg, A. D. Gruber, H. Gehlen   +7 more
wiley   +1 more source