Results 201 to 210 of about 409,120 (302)

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

open access: yesThe FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi   +12 more
wiley   +1 more source

A multicentre evaluation of cardiovascular risk prediction tools in people living with HIV across England (ECARTH study)

open access: yesHIV Medicine, EarlyView.
Abstract Introduction It remains unclear which cardiovascular disease (CVD) risk scores are optimized for people living with treated HIV with high rates of viral suppression. We evaluated the performance of commonly used CVD risk scores in a population of primarily well‐treated HIV patients in England.
Ming Jie Lee   +23 more
wiley   +1 more source

Prospective use of genomics in the evaluation of sudden cardiac death: results from a national health service population pathway. [PDF]

open access: yesEBioMedicine
Wade C   +17 more
europepmc   +1 more source

Rebuilding the Women's Estate: Imaginary Penalities in Scottish Imprisonment, 2012–2023

open access: yesThe Howard Journal of Crime and Justice, EarlyView.
ABSTRACT This article explores a period during which the Scottish Prison Service aspired to a ‘golden age’ for imprisonment, tracing how a narrative of progress shaped a decade of struggle to close Scotland's national prison for women: ‘Cornton Vale’.
Cara Hunter
wiley   +1 more source

Diagnostic relevance of angiography-derived coronary microcirculatory resistance in sudden cardiac death. [PDF]

open access: yesQuant Imaging Med Surg
Sedoud B   +11 more
europepmc   +1 more source

Optimal Hypoxia Mimetic Small Molecules for Enhancing Angiogenic Properties of Stem Cells From Human Exfoliated Deciduous Teeth

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang   +9 more
wiley   +1 more source

Australasian chronic lymphocytic leukaemia consensus statement: 2026 update

open access: yesInternal Medicine Journal, EarlyView.
Abstract In 2023, a consensus statement on the diagnosis and management of chronic lymphocytic leukaemia (CLL) in Australasia was published. Since then, advances in clinical evidence and increased availability of molecular diagnostics and targeted therapies have further influenced contemporary CLL management.
Sean McKeague   +27 more
wiley   +1 more source

Relatives' Experiences of Circulatory Death Following Out‐of‐Hospital Cardiac Arrest and Their Hypothetical Perspectives on Organ Donation: A Qualitative Study

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aims To explore relatives' experiences of the circulatory death of a family member following out‐of‐hospital cardiac arrest and to explore their hypothetical perspectives on being asked to decide about organ donation in this situation. This study forms part of a broader initiative undertaken to assess the prerequisites for implementing ...
Gisela Vogel   +3 more
wiley   +1 more source

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