Results 71 to 80 of about 22,016 (288)

Comparative assessment of artificial intelligence chatbots' performance in responding to healthcare professionals' and caregivers' questions about Dravet syndrome

Epilepsia Open, EarlyView.
Abstract Objective Artificial intelligence chatbots have been a game changer in healthcare, providing immediate, round‐the‐clock assistance. However, their accuracy across specific medical domains remains under‐evaluated. Dravet syndrome remains one of the most challenging epileptic encephalopathies, with new data continuously emerging in the ...
Joana Jesus‐Ribeiro, Eugenia Roza, Bárbara Oliveiros, Joana Barbosa Melo, Mar Carreño   +4 more
wiley   +1 more source

Epilepsy syndromes classification

Epilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell, Nicola Specchio, Rima Nabbout, Phillip L. Pearl, Kate Riney   +4 more
wiley   +1 more source

Altered brain connectivity in sudden unexpected death in epilepsy (SUDEP) revealed using resting-state fMRI. [PDF]

, 2019
The circumstances surrounding SUDEP suggest autonomic or respiratory collapse, implying central failure of regulation or recovery. Characterisation of the communication among brain areas mediating such processes may shed light on mechanisms and ...
B, Diehl, Ca, Scott, Ja, Ogren, L, Lemieux, LA, Allen, M, Guye, R, Kumar, Rm, Harper, S, Ourselin, Sb, Vos, Sd, Lhatoo   +10 more
core  

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

Nonseizure symptoms and broader seizure impacts in patients with Dravet syndrome and Lennox–Gastaut syndrome in clinical practice settings: Results from a multinational survey

Epilepsia Open, EarlyView.
Abstract Objective To assess the burden of Dravet syndrome (DS) and Lennox–Gastaut syndrome (LGS), including managing seizure and nonseizure symptoms, on patients and caregivers. Methods Data were drawn from the Adelphi Real World DS and LGS Disease Specific Programme™, a cross‐sectional survey in Asia (China, Japan), Europe (France, Germany, Italy ...
Drishti Shah, Vicente Villanueva, Dennis Dlugos, Arturo Benitez, Yasmin Taylor, Stevie Olsen, Hannah Connolly, Sophie Lai, J. Scott Andrews   +8 more
wiley   +1 more source

Modulation of autonomic activity in neurological conditions: Epilepsy and Tourette Syndrome [PDF]

, 2015
This manuscript considers the central but neglected role of the autonomic nervous system in the expression and control of seizures in epilepsy (small) and tics in Tourette Syndrome (TS).
Antebi, Bauscein, Berilgen, Blumenfeld, Casper, Chatrian, Craig, Critchley, Drake, Evrengül, Fenwick, Gianaros, Gowers, Gray, Hoekstra, Hopkins, Janig, Lockard, Micoulaud-Franchi, Miller, Mraovitch, Nagai, Nagai, Nagai, Nagai, Nagai, Nagai, Nagai, Nagai, Nagai, Nagai, Nakken, Naqvi, Nashef, Ottaviani, Persson, Petitmengin, Pinikahana, Poh, Price, Ridsdale, Robertson, Schraeder, Shwartz, Spector, Steinberg, Steinberg, Surges, Swerdlow, Tolstykh, Tulen, van Dijk, Wang, Wood, Wyler, Yoko Nagai, Zaatreh   +56 more
core   +2 more sources

Sudden, unexpected death in epilepsy in children

Seizure, 1997
Sudden, unexpected death in epilepsy (SUDEP) remains a controversial and enigmatic syndrome, particularly in children where the incidence, prevalence and risk factors may, and probably do, differ from adults. This study demonstrates (and further reinforces) the difficulties and inability of retrospective and coroner/death certificate-derived data in ...
openaire   +3 more sources

Seizures beget more than seizures: Understanding the cellular, structural, individual and societal impact of seizures in epilepsy

Epilepsia Open, EarlyView.
Abstract Epilepsy is primarily defined by the repetitive occurrence of seizures, but the full impact of seizures extends beyond these episodic events. Seizures themselves cause changes at the cellular, network, and systemic levels in individual patients with epilepsy and may contribute to the progressive nature of the disease in some patients. Seizures
Matthew C. Walker, Marian Galovic, Elena Álvarez‐Barón, Adam Strzelczyk   +3 more
wiley   +1 more source

Possible role of SCN4A skeletal muscle mutation in apnea during seizure

Epilepsia Open, 2019
SCN4A gene mutations cause a number of neuromuscular phenotypes including myotonia. A subset of infants with myotonia‐causing mutations experience severe life‐threatening episodic laryngospasm with apnea.
Dilşad Türkdoğan, Emma Matthews, Sunay Usluer, Aslı Gündoğdu, Kayıhan Uluç, Roope Mannikko, Michael G. Hanna, Sanjay M. Sisodiya, Hande S. Çağlayan   +8 more
doaj   +1 more source

Are there mortality risks for patients with epilepsy who use cannabis treatments as monotherapy?

Epilepsy and Behavior Case Reports, 2019
Mortality associated with cannabis used for treatment of epilepsy is not well documented. We discuss two fatalities in the setting of epilepsy and self-determined therapy with cannabis (SDTC). One patient had probable sudden unexpected death in epilepsy,
Devon M. Kollmyer, Kyla E. Wright, Nicole M. Warner, Michael J. Doherty   +3 more
doaj   +1 more source