Results 41 to 50 of about 5,831 (244)
Genome-wide Polygenic Burden of Rare Deleterious Variants in Sudden Unexpected Death in Epilepsy
EBioMedicine, 2015 Sudden unexpected death in epilepsy (SUDEP) represents the most severe degree of the spectrum of epilepsy severity and is the commonest cause of epilepsy-related premature mortality.
Costin Leu +31 more
doaj +1 more source
Frontiers in Neurology, 2023 Background and objectiveSudden unexpected death in epilepsy (SUDEP) has been regarded as a leading cause of premature death in patients with epilepsy (PWE).
Yuanhang Pan +12 more
doaj +1 more source
Seizures, Cerebral Shutdown, and SUDEP [PDF]
Epilepsy Currents, 2013 Several potential pathophysiologic phenomena, including “cerebral shutdown,” are postulated to be responsible for SUDEP. Since the evidence for a seizure-related mechanism is strong, a poor understanding of the physiology of human seizure termination is a major handicap.
Alireza Bozorgi, Samden D. Lhatoo
openaire +3 more sources
The brain–heart interaction in epilepsy: implications for diagnosis, therapy, and SUDEP prevention
Annals of Clinical and Translational Neurology, 2021 The influence of the central nervous system and autonomic system on cardiac activity is being intensively studied, as it contributes to the high rate of cardiologic comorbidities observed in people with epilepsy. Indeed, neuroanatomic connections between
Giorgio Costagliola +5 more
semanticscholar +1 more source
Risk Assessment for Sudden Death in Epilepsy: The SUDEP-7 inventory
Frontiers in Neurology, 2015 Background: Sudden Unexpected Death in Epilepsy (SUDEP) is a major cause of death in those with drug resistant epilepsy. There is a need for inventories and biomarkers associated with the risk for SUDEP.
Jennifer L Novak +4 more
doaj +1 more source
Cortical neuronal hypertrophy and mTOR pathway activation in CAN regions in SUDEP
Epilepsia, 2022 Dysfunctional connectivity and preexisting structural abnormalities of central autonomic network (CAN) regions have been shown on magnetic resonance imaging (MRI) in sudden unexpected death in epilepsy (SUDEP) and may be mechanistically relevant.
S. Patodia +5 more
semanticscholar +1 more source
Frontiers in Neurology, 2019 Sudden unexpected death in epilepsy (SUDEP) is a leading cause of abrupt death in patient with epilepsy. It represents 5–30% of all rapid deaths in individuals with epilepsy.
Yandong Ren +7 more
doaj +1 more source
Maternal Death Related to Sudden Unexpected Death in Epilepsy: A Nationwide Survey in Japan
Brain Sciences, 2021 Sudden unexpected death in epilepsy (SUDEP) is defined as the sudden death of a patient with epilepsy in the absence of an anatomic or toxicologic cause. Whether pregnancy is a risk factor for SUDEP is unclear.
Hiroaki Tanaka +9 more
doaj +1 more source
Genetic Basis of Sudden Unexpected Death in Epilepsy
Frontiers in Neurology, 2017 People with epilepsy are at heightened risk of sudden death compared to the general population. The leading cause of epilepsy-related premature mortality is sudden unexpected death in epilepsy (SUDEP).
Richard D. Bagnall +6 more
doaj +1 more source
SUDEP, the aftermath: supporting the bereaved [PDF]
Practical Neurology, 2017 Sudden unexpected death in epilepsy is a recurring calamity, yet there is little evidence to guide standards of care for supporting the bereaved. Grief in bereavement includes loss, feelings of guilt, anger and blame. There is also the shock and trauma of the sudden event. How can this be alleviated?
Nashef, Lina, Leach, John Paul
openaire +3 more sources