Results 71 to 80 of about 4,113 (218)

Unilateral ultra long‐term subcutaneous EEG monitoring in drug‐refractory idiopathic generalized epilepsy

Epilepsia, EarlyView.
Abstract Objective Seizure self‐reporting is known to be unreliable, particularly with non‐convulsive seizures. There is increasing interest in long‐term monitoring systems to detect and count seizures, including the use of the minimally‐invasive CE‐marked subcutaneous unilateral electroencephalography (EEG) recording system, which has been shown to ...
Tudor Munteanu, Bryoni Daly, Cara O'Donnell, Annette Breen, Tenzin Choekyi, Breege Staunton‐Grufferty, Donncha O'Brien, Kieron Sweeney, Ronan Kilbride, Peter Widdess‐Walsh, Hany El‐Naggar, Norman Delanty   +11 more
wiley   +1 more source

Dead in the Night: Sleep-Wake and Time-Of-Day Influences on Sudden Unexpected Death in Epilepsy

Frontiers in Neurology, 2018
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of epilepsy-related death in patients with refractory epilepsy. Convergent lines of evidence suggest that SUDEP occurs due to seizure induced perturbation of respiratory, cardiac, and ...
Benton S. Purnell, Benton S. Purnell, Benton S. Purnell, Roland D. Thijs, Roland D. Thijs, Roland D. Thijs, Gordon F. Buchanan, Gordon F. Buchanan, Gordon F. Buchanan   +8 more
doaj   +1 more source

Artificial intelligence‐driven closed‐loop devices in sudden unexpected death in epilepsy prediction and prevention: Insights from persons with epilepsy and caregivers

Epilepsia, EarlyView.
Abstract Objective The absence of strategies for predicting and preventing sudden unexpected death in epilepsy (SUDEP) is intertwined with the lack of studies measuring users' attitudes toward potential innovative interventions. The NEUROSENSE Project (http://www.neurosense‐project.eu) aims to evaluate novel SUDEP‐predictive neuroendocrine biomarkers ...
João Ferreira, Miguel França, Mariana Cardoso Regalo, Mariana Rei, Ricardo Peixoto, José Ángel Aibar, Torie Robinson, Ricardo Matias, Fabrice Duprat, Massimo Mantegazza, Onur Parlak, Philippe Ryvlin, Sándor Beniczky, Lígia Lopes, Emilio Perucca, João Claro, Carlos Conde   +16 more
wiley   +1 more source

Categorisation of EEG suppression using enhanced feature extraction for SUDEP risk assessment [PDF]

, 2020
Juan C. Mier, Yejin Kim, Xiaoqian Jiang, Guo‐Qiang Zhang, Samden D. Lhatoo   +4 more
openalex   +1 more source

A global perspective on transitioning from pediatric to adult care in epilepsy

Epilepsia, EarlyView.
Abstract Objective Transition planning in epilepsy is crucial to ensure continuity of care, particularly for adolescents with complex needs, yet global practices remain undefined. The International League Against Epilepsy Transition Task Force (ILAE TTF) aimed to evaluate worldwide practices, barriers, and provider perspectives on transitioning ...
Danielle M. Andrade, Nathalie Jetté, Ilakkiah Chandran, Puja Patel, Guido Rubboli, J. Helen Cross, Dana Craiu, Chong Tin Tan, Edward Kija, Eva Fung, Tiziana Granata, Hassan Hosny, Marco Mula, Kate Riney, Renée A. Shellhaas, Maria Siddiqui, Quratulain Zulfiqar Ali, Julien Hébert, Paula Marques, Bronte Kerrigan, Caihong Ji, Kette Valente, Jaime Carrizosa, Rima Nabbout   +23 more
wiley   +1 more source

Clinical risk factors in SUDEP [PDF]

, 2020
Mar, M Zuluaga, S Otero-Romero, A Rovira, M Tintore, Rovira, J Ro, R Bermel, X You, P Foulds, V Jokubaitis, T Spelman, T Kalincik, K Hellwig, M Rockhoff, S Herbstritt, H Patel, A Kumar, G Raymond, G Mainali, P Pouwels, A Vanderver, G Bernard, M Van Der Knaap, R Schiffmann, F Mochel, N Wolf, M Van Der Knaap, I Boor, R Estvez, T Yamamoto, S Shimada, K Shimojima, A Espay, S Ries, T Maloney, O Sveinsson, T Andersson, P Mattsson, S Carlsson, T Tomson, S Cumming, C Jimenez-Moreno, K Okkersen   +43 more
openalex   +1 more source

Loss-of-function variants in the cardiac K _v 11.1 channel as a genetic biomarker for SUDEP [PDF]

, 2021
Ming S. Soh, Richard D. Bagnall, Mark F. Bennett, Lauren E. Bleakley, Erlina S. Mohamed Syazwan, A. Marie Phillips, Mathew D. F. Chiam, Chaseley E. McKenzie, Michael S. Hildebrand, Douglas E. Crompton, Melanie Bahlo, Christopher Semsarian, Ingrid E. Scheffer, Samuel F. Berkovic, Christopher A. Reid   +14 more
openalex   +1 more source

Respiratory dysfunction and fatal apnea during pilocarpine‐induced status epilepticus

Epilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is second only to sudden unexpected death in epilepsy as a cause of seizure‐related mortality. The progression of respiratory dysfunction during experimental SE remains poorly characterized. We investigated how pilocarpine‐induced SE affects respiration in mice.
Chengsan Sun, Rachel Spera, John M. Williamson, Suchitra Joshi, Bhavya Guduru, Harini Ganabady, Jaideep Kapur   +6 more
wiley   +1 more source

Bexicaserin for the treatment of seizures in developmental and epileptic encephalopathies: A phase 1b/2a trial (PACIFIC)

Epilepsia, EarlyView.
Abstract Objective This randomized, double‐blind, phase 1b/2a clinical trial was designed to evaluate the safety, tolerability, and efficacy of oral bexicaserin versus placebo for the treatment of seizures in adolescents and adults with developmental and epileptic encephalopathies (DEEs).
Dennis J. Dlugos, Ingrid E. Scheffer, Jacqueline A. French, David G. Vossler, Chad Orevillo, Shikha Polega, Randall Kaye, and the LP352‐201 Study Investigators, Kore Liow, Ena Zhu, Jennifer Waldron, Hayley Groubert, Alexis Anderson, Pavel Klein, Salman Hashmi, Shicong Ye, Anita Farhi, David Vossler, Dione M. Froman, Shannon L. Hoffman‐Huffaker, Ki Hyeong Lee, AnnaLyn Dallas, Amir Arain, Laura Beeler, Michael Macken, Irena Bellinski, Elizabeth Cunningham, James Renfroe, Shezsay Colbert, Robert Hogan, Patty Schaefer, Susan Shaw, Sheetal Desai, Ahmed Sadek, Haile Robertson, Kamil Detyniecki, Anabela Cieslicki, Ruben Kuzniecky, Sarah Goodman, Selim Benbadis, Marina Azevedo, Sami Aboumatar, Julie Biel, Nilika Singhal, Emerald Wan, Evan Fertig, Hannah Hart, Debopam Samanta, Sarah Hankins, Steven Wolf, Patricia Pena, Robert Nahouraii, M. J. Mari, David Burdette, Stephanie Mueller, Karen Keough, Victoria Henderson, Talitha Durgin, Terence O’Brien, Rafael Smith, Jack Germaine, Kate Riney, Lori Anthony, David Reutens, Kimberley Irwin, Michael Fahey, Melissa Batt, Stephanie Kaladis, Kasthoori Jeyachanthiran, Ingrid Scheffer, Rebecca Wharrie, Greesha Zacharia, Brittany Walsh, Heather Robinson, Sharon Ganter   +74 more
wiley   +1 more source

Hypothalamic-pituitary-adrenal axis dysfunction worsens epilepsy outcomes and increases SUDEP risk [PDF]

, 2022
Trina Basu, Pantelis Antonoudiou, Grant L. Weiss, Daniel Friedman, Juliana Laze, Orrin Devinsky, Jamie Maguire   +6 more
openalex   +1 more source