Results 51 to 60 of about 2,404,149 (283)
On the Metaphysical Necessity of Suffering from Natural Evil [PDF]
, 2013 Why does God permit suffering in the world? If God is wholly good, omnipotent, and omniscient, why would He not intervene to prevent us from suffering?
Sullivan, Ryan Edward
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
First, do no harm: The patient's experience of avoidable suffering as harm
Patient Experience Journal, 2018 Although my entire career has been spent in Patient Experience, nothing I have learned from data, evidence-based practice, or experience-based correlations, has been near as impactful as what I learned from being a patient.
Ashley Bauer
doaj
Close, but not close enough? Audience’s reactions to domesticated distant suffering in international news coverage [PDF]
, 2017 The interest in audience responses to mediated distant suffering has been growing in the last decade. Earlier research about the mediation of distant suffering was often morally or theoretically based, or textually informed and recent empirical research ...
Huiberts, Eline, Joye, Stijn
core +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Superintelligence as a Cause or Cure for Risks of Astronomical Suffering [PDF]
, 2017 Discussions about the possible consequences of creating superintelligence have included the possibility of existential risk, often understood mainly as the risk of human extinction. We argue that suffering risks (s-risks) , where an adverse outcome would
Gloor, Lukas, Sotala, Kaj
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Relations and Moral Obligations towards Other Animals
Relations, 2015 Relational accounts acknowledge and emphasise the intersubjective nature of selfhood and argue that focusing solely on the capacities of animals cannot account for all moral obligations towards them.
Beril Sözmen
doaj +1 more source
One Big Thing: Suffering as the Path to New Life in Crime and Punishment [PDF]
, 2015 After spending a whole semester reading and thinking about Dostoevsky, the main thing that has struck me about him is his treatment of the theme of suffering.
Kramer, Kelly M
core +1 more source