Results 61 to 70 of about 1,019,017 (316)

Erinys’ Mortal Venom: The Poetic Expression of Emotions in Silius Italicus’ "Punica" (Books I–V)

open access: yesClassica Cracoviensia, 2018
Erinys’ Mortal Venom: The Poetic Expression of Emotions in Silius Italicus’ "Punica" (Books I–V) Negative emotions are used to construct and develop the plot in the first five books of Silius Italicus’ Punica. Dark, irrational forces, i.e.
Stanisław Śnieżewski
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A New Method For Measuring and Analyzing Suffering. Comparing Suffering in Italian Society

open access: yes, 2015
In this study, we introduce an innovative methodology for fuzzy measuring multidimensional subjective suffering, based on ordinal data. We apply the methodology to data about suffering in Italy, for years 2007 and 2010. The analysis reveals the existence
Fattore M., MAGGINO, FILOMENA
core   +1 more source

Illness and the Politics of Social Suffering: Towards a Critical Research Agenda in Health and Science Studies

open access: yesRevista Crítica de Ciências Sociais, 2018
This article analyses some of the emerging problems in the field of social studies at the juncture of the domains of health and science. Building on critical perspectives, namely those hailing from social history, postcolonial studies and collaborative ...
Tiago Pires Marques
doaj   +1 more source

Enough Suffering: Thoughts on Suffering and Virtue [PDF]

open access: yesThe Journal of Value Inquiry, 2021
Coplan, Amy, Battaly, Heather
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Suffering

open access: yes, 2015
The topic of suffering encompasses an enormous range of issues. In this discussion the focus will be is on two key sets of questions: the nature and definition of suffering and the nature of the responses to suffering. At its broadest, suffering is taken
Jeffery Malpas (14743243)
core  

Why we should not postpone awareness of wild animal suffering

open access: yes, 2016
Ng (2016) restates his case for the importance of wild animal suffering (1995). Nevertheless, he suggests that the most effective way to reduce nonhuman suffering overall is to give short-term priority to the suffering of farmed animals.
Pacheco Faria, Catia Gisela
core   +1 more source

Suffering [PDF]

open access: yesMedicine, Health Care and Philosophy, 2020
Bert, Gordijn, Henk, Ten Have
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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