Results 81 to 90 of about 2,426,055 (315)

Specular suffering: (staging) the body in pain [PDF]

open access: yes, 2008
For the abstract see the PDF ...
Richards, M
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The spiral relationship between suffering and the production of fashionable clothes [PDF]

open access: yes, 2014
In this article, I explore relationships between suffering and the production of fashionable clothes. In the commercial struggle for survival many fashionable styles are discarded while some remain durable due to their adaptability to new trends and ...
Almond, Kevin
core   +1 more source

Gender and sufferings

open access: yesJournal of Obstetrics and Gynaecology, 2005
The World Health Organization describes violence against women, as the most pervasive yet least recognised human rights abuse which cuts across geographical, racial, social and economic boundaries in the world. In the present study of the 2000 women interviewed, nearly 50% reported having been physically assaulted.
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

”Whatever Does Not Kill Me Makes Me Stronger”: A Sociological Analysis of Uses of the Concept of Resilience. The Case of Boris Cyrulnik’s Self-Help Books Readers

open access: yesSwiss Journal of Sociology, 2019
This article offers a social science analysis of the resilience concept’s success and common sense uses. Based on a sample of letters from the readers of the French author Boris Cyrulnik’s self-help best-sellers, the article first depicts the ...
Marquis Nicolas
doaj   +1 more source

Dysthanasia [PDF]

open access: yesScripta Medica
Dysthanasia in medicine is the artificial prolongation and delay of death in a terminal patient, using all available means. With the advancement of sophisticated medical technologies and care, the patient can be kept alive as long as possible in the ...
Greš Alen   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Icons of Just Is: Justice, Suffering, and the Artwork of Samuel Bak

open access: yesReligions, 2017
This paper examines select paintings by Holocaust survivor and painter Samuel Bak from his recent Just Is series. The essay explores ways Bak’s art bears witness to suffering.
Gary A. Phillips
doaj   +1 more source

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