Results 71 to 80 of about 2,407,462 (283)

Learning To Be Affected: Social suffering and total pain at life’s borders. [PDF]

, 2012
The practice of Live Sociology in situations of pain and suffering is the author’s focus. An outline of the challenges of understanding pain is followed by a discussion of Bourdieu’s ‘social suffering’ (1999) and the palliative care philosophy of ‘total ...
Ahmed S., Ahmed S., Back L., Badiou A., Bar-On D., Bourdieu P., Brown G., Butler J., Calarco M., DeLanda M., Derrida J., Derrida J., Gordon A., Gunaratnam Y., Hagglund M., Harman G., Keats J., Lawton J., Levinas E., Saunders C. M., Saunders C. M., Saunders C. M., Scarry E., Shields R., Stanworth R., Turner B. S., Waddell M., Weber M., Wyschogrod E., Yasmin Gunaratnam   +29 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Marie Uguay et Saint-Denys Garneau, au bord du vide

Conserveries Mémorielles, 2010
This is a comparative analysis of the works of two Quebecois poets, Saint-Denys Garneau and Marie Uguay who have many common points.  Both express a conscience and a lucid vision of death. Their poetic works show that their lyric subjects are situated in
Mylène Durand
doaj  

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Pozorny smutek sprawiedliwego w Księdze Mądrości

Studia Koszalińsko-Kołobrzeskie, 2016
The article analyzes the issue of the suffering of a righteous man in the part I of the Book of Wisdom. It is often treated by the exegetes as a sad reality that affects the just, yet after a careful analysis it turns out to be apparent. The text’s
Marcin Zieliński
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Back to Basics: Human Rights and the Suffering Imperative [PDF]

, 2008
Anniversaries provide a conventionally appropriate opportunity to take stock and, where necessary, to remind ourselves of why we hold to the commitments we do.
Fagan, A
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On the media construction of international disasters [PDF]

, 2014
For most people living in western countries, disasters are a priori cases of distant suffering as they mainly affect cultural or ethnic others. News media thus play a pivotal role in giving publicity and meaning to the numerous instances of global ...
Joye, Stijn
core