Results 71 to 80 of about 2,404,149 (283)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Pozorny smutek sprawiedliwego w Księdze Mądrości

open access: yesStudia Koszalińsko-Kołobrzeskie, 2016
The article analyzes the issue of the suffering of a righteous man in the part I of the Book of Wisdom. It is often treated by the exegetes as a sad reality that affects the just, yet after a careful analysis it turns out to be apparent. The text’s
Marcin Zieliński
doaj   +1 more source

Taking a New Perspective on Suffering and Death [PDF]

open access: yes, 2019
There is a massive amount of severe suffering and death in the world, and much of this suffering and death is out of our control. The amount and severity of suffering and death in the world can be used to make an argument for (or elicit a reaction ...
Tweedt, Chris
core   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

On the media construction of international disasters [PDF]

open access: yes, 2014
For most people living in western countries, disasters are a priori cases of distant suffering as they mainly affect cultural or ethnic others. News media thus play a pivotal role in giving publicity and meaning to the numerous instances of global ...
Joye, Stijn
core  

Serum beta-glucuronidase determination in normal subjects and in neurological and mental patients, a provisional report [PDF]

open access: yes, 1963
Using the method given by GOLDSTEIN (1961)9 for the determination of serum beta-glucuronidase activity, this value was determined in both normal and patients with epilepsy, neuroses, psychoses and multiple sclerosis.
Plum, Claus Munk
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

”Whatever Does Not Kill Me Makes Me Stronger”: A Sociological Analysis of Uses of the Concept of Resilience. The Case of Boris Cyrulnik’s Self-Help Books Readers

open access: yesSwiss Journal of Sociology, 2019
This article offers a social science analysis of the resilience concept’s success and common sense uses. Based on a sample of letters from the readers of the French author Boris Cyrulnik’s self-help best-sellers, the article first depicts the ...
Marquis Nicolas
doaj   +1 more source

Dysthanasia [PDF]

open access: yesScripta Medica
Dysthanasia in medicine is the artificial prolongation and delay of death in a terminal patient, using all available means. With the advancement of sophisticated medical technologies and care, the patient can be kept alive as long as possible in the ...
Greš Alen   +2 more
doaj   +1 more source

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