Results 71 to 80 of about 845,542 (252)

Semiparametric Causal Sufficient Dimension Reduction Of High Dimensional Treatments

, 2020
Cause-effect relationships are typically evaluated by comparing the outcome responses to binary treatment values, representing two arms of a hypothetical randomized controlled trial. However, in certain applications, treatments of interest are continuous
McNutt, Todd, Nabi, Razieh, Shpitser, Ilya   +2 more
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Plugin procedure in segmentation and application to hyperspectral image segmentation

, 2010
In this article we give our contribution to the problem of segmentation with plug-in procedures. We give general sufficient conditions under which plug in procedure are efficient. We also give an algorithm that satisfy these conditions.
Girard, R.
core   +3 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

On Weighted Multivariate Sign Functions

, 2020
Multivariate sign functions are often used for robust estimation and inference. We propose using data dependent weights in association with such functions.
Chatterjee, Snigdhansu, Majumdar, Subhabrata   +1 more
core  

Dynamic Partial Sufficient Dimension Reduction

, 2019
Sufficient dimension reduction aims for reduction of dimensionality of a regression without loss of information by replacing the original predictor with its lower-dimensional subspace. Partial (sufficient) dimension reduction arises when the predictors naturally fall into two sets, X and W, and we seek dimension reduction on X alone while considering ...
Li, Lu, Tan, Kai, Wen, Xuerong Meggie, Yu, Zhou   +3 more
openaire   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

The Alternating Direction Method of Multipliers for Sufficient Dimension Reduction

Journal of Mathematics
The minimum average variance estimation (MAVE) method has proven to be an effective approach to sufficient dimension reduction. In this study, we apply the computationally efficient optimization algorithm named alternating direction method of multipliers
Sheng Ma, Qin Jiang, Zaiqiang Ku
doaj   +1 more source

Impact of informational dimension and information on the operation cost [PDF]

Војно дело, 2014
Despite the disappearance of the bipolar world, the mankind has not yet become free from challenges, risks and threats to peace and security. Armed conflicts have remained a part of reality, and new security challenges, risks and threats have emerged ...
Miladinović Mića, Šipka Branko
doaj   +1 more source