Results 41 to 50 of about 105,654 (223)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
An Analog-Digital Hardware for Parzen-Based Nonparametric Probability Density Estimation
IEEE AccessProbability estimation measures the likelihood of different outcomes in a statistical context. It commonly involves estimating either the parameters or the entire distribution of a random variable.
Djordje Stankovic +4 more
doaj +1 more source
ENHANCING RURAL LIVELIHOODS THROUGH SUSTAINABLE LAND AND WATER MANAGEMENT IN NORTHWEST ETHIOPIA
Geography, Environment, Sustainability, 2015 Rural livelihoods (RLs) in highland Ethiopia is critically threatened by increasing degradation of land and water resources (LWRs) and lack of sufficient livelihood assets.
Mehretie Belay, Woldeamlak Bewket
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Remote SensingThe Vietnam Mekong River Delta (VMRD) is a climate-sensitive region characterized by diverse ecosystems, including extensive mangrove forests that protect against sea-level rise and contribute to global carbon sequestration.
Hai-An Bui +4 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Brickwall one-loop determinant: spectral statistics & Krylov complexity
Journal of High Energy PhysicsWe investigate quantum chaotic features of the brickwall model, which is obtained by introducing a stretched horizon — a Dirichlet wall placed outside the event horizon — within the BTZ geometry.
Hyun-Sik Jeong +2 more
doaj +1 more source
AerospaceAdvanced Aerial Mobility (AAM) platforms are poised to begin high-density operations in urban areas nationwide. This new category of aviation platforms spans a broad range of sizes, from small package delivery drones to passenger-carrying vehicles ...
Zack Krawczyk +3 more
doaj +1 more source