Results 41 to 50 of about 930,221 (249)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

An Analog-Digital Hardware for Parzen-Based Nonparametric Probability Density Estimation

IEEE Access
Probability estimation measures the likelihood of different outcomes in a statistical context. It commonly involves estimating either the parameters or the entire distribution of a random variable.
Djordje Stankovic, Andjela Draganic, Nedjeljko Lekic, Cornel Ioana, Irena Orovic   +4 more
doaj   +1 more source

ENHANCING RURAL LIVELIHOODS THROUGH SUSTAINABLE LAND AND WATER MANAGEMENT IN NORTHWEST ETHIOPIA

Geography, Environment, Sustainability, 2015
Rural livelihoods (RLs) in highland Ethiopia is critically threatened by increasing degradation of land and water resources (LWRs) and lack of sufficient livelihood assets.
Mehretie Belay, Woldeamlak Bewket
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Advanced Semi-Supervised Learning for Remote Sensing-Based Land Cover Classification in the Mekong River Delta, Vietnam

Remote Sensing
The Vietnam Mekong River Delta (VMRD) is a climate-sensitive region characterized by diverse ecosystems, including extensive mangrove forests that protect against sea-level rise and contribute to global carbon sequestration.
Hai-An Bui, Chih-Hua Hsu, Hsu-Wen Vincent Young, Yi-Ying Chen, Yuei-An Liou   +4 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Brickwall one-loop determinant: spectral statistics & Krylov complexity

Journal of High Energy Physics
We investigate quantum chaotic features of the brickwall model, which is obtained by introducing a stretched horizon — a Dirichlet wall placed outside the event horizon — within the BTZ geometry.
Hyun-Sik Jeong, Arnab Kundu, Juan F. Pedraza   +2 more
doaj   +1 more source

Evaluating Reduced-Order Urban Wind Models for Simulating Flight Dynamics of Advanced Aerial Mobility Aircraft

Aerospace
Advanced Aerial Mobility (AAM) platforms are poised to begin high-density operations in urban areas nationwide. This new category of aviation platforms spans a broad range of sizes, from small package delivery drones to passenger-carrying vehicles ...
Zack Krawczyk, Rohit K. S. S. Vuppala, Ryan Paul, Kursat Kara   +3 more
doaj   +1 more source