Results 51 to 60 of about 105,964 (266)

Beyond Pairs: Generalizing the Geo-dipole for Quantifying Spatial Patterns in Geographic Fields [PDF]

open access: yes, 2017
With their increasing availability and quantity, remote sensing images have become an invaluable data source for geographic research and beyond. The detection and analysis of spatial patterns from such images and other kinds of geographic fields ...
Rui Zhu   +6 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

A new approach to spatial data interpolation using higher-order statistics [PDF]

open access: yes, 2014
Interpolation techniques for spatial data have been applied frequently in various fields of geosciences. Although most conventional interpolation methods assume that it is sufficient to use first- and second-order statistics to characterize random fields,
Wolff, Rodney C.   +4 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Midnight sector observations of auroral omega bands [PDF]

open access: yes, 2011
We present observations of auroral omega bands on 28 September 2009. Although generally associated with the substorm recovery phase and typically observed in the morning sector, the features presented here occurred just after expansion phase onset and ...
Fear, R.C.   +41 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Linear and Parallel Learning of Markov Random Fields [PDF]

open access: yes, 2014
We introduce a new embarrassingly parallel parameter learning algorithm for Markov random fields which is efficient for a large class of practical models. Our algorithm parallelizes naturally over cliques and, for graphs of bounded degree, its complexity
Nando De Freitas   +1 more
core   +2 more sources

Advanced Semi-Supervised Learning for Remote Sensing-Based Land Cover Classification in the Mekong River Delta, Vietnam

open access: yesRemote Sensing
The Vietnam Mekong River Delta (VMRD) is a climate-sensitive region characterized by diverse ecosystems, including extensive mangrove forests that protect against sea-level rise and contribute to global carbon sequestration.
Hai-An Bui   +4 more
doaj   +1 more source

Linear Algebra and Smarandache Linear Algebra [PDF]

open access: yes, 2003
The present book, on Smarandache linear algebra, not only studies the Smarandache analogues of linear algebra and its applications, it also aims to bridge the need for new research topics pertaining to linear algebra, purely in the algebraic sense.
Vasantha, Kandasamy
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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