Results 51 to 60 of about 924,189 (253)
A comparison of minimum MSE and maximum power for the nearly integrated non-Gaussian model [PDF]
, 2000 We study the optimal choice of quasi-likelihoods for nearly integrated,possibly non-normal, autoregressive models. It turns out that the two mostnatural candidate criteria, minimum Mean Squared Error (MSE) and maximumpower against the unit root null ...
Abadir, K.M., Lucas, A.
core +2 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Brickwall one-loop determinant: spectral statistics & Krylov complexity
Journal of High Energy PhysicsWe investigate quantum chaotic features of the brickwall model, which is obtained by introducing a stretched horizon — a Dirichlet wall placed outside the event horizon — within the BTZ geometry.
Hyun-Sik Jeong +2 more
doaj +1 more source
The advent of increasingly advanced surveys and cosmic tracers has motivated the development of new inference techniques and novel approaches to extracting information from cosmic fields. A central challenge in this endeavor is to quantify the information content carried by these summary statistics in cosmic fields.
Sui, Ce +4 more
openaire +2 more sources
Spatial modelling for mixed-state observations
, 2008 In several application fields like daily pluviometry data modelling, or motion analysis from image sequences, observations contain two components of different nature.
Hardouin, Cécile, Yao, Jian-Feng
core +3 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Approximate Bayesian Computational methods
, 2011 Also known as likelihood-free methods, approximate Bayesian computational (ABC) methods have appeared in the past ten years as the most satisfactory approach to untractable likelihood problems, first in genetics then in a broader spectrum of applications.
Marin, Jean-Michel +3 more
core +3 more sources
Resolving the fine-scale structure in turbulent Rayleigh-Benard convection [PDF]
, 2013 We present high-resolution direct numerical simulation studies of turbulent Rayleigh-Benard convection in a closed cylindrical cell with an aspect ratio of one. The focus of our analysis is on the finest scales of convective turbulence, in particular the
Emran, Mohammad S. +2 more
core +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
A Review of the Literature on Patellar Tendinopathy: Current State of Knowledge
Quality in SportIntroduction: Patellar tendinopathy, commonly referred to as jumper’s knee, presents as pain and dysfunction in the patellar tendon, predominantly affecting athletes engaged in jumping sports.
Jakub Milczarek +9 more
doaj +1 more source