Sugammadex for reversal of neuromuscular blockade: a retrospective analysis of clinical outcomes and cost-effectiveness in a single center [PDF]
Michele Carron, Fabio Baratto, Francesco Zarantonello, Carlo Ori Department of Medicine, Anesthesiology and Intensive Care, University of Padova, Padova, Italy Objective: The aim of the study is to evaluate the clinical and economic impact of introducing
Carron M +3 more
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Prediction of Optimal Reversal Dose of Sugammadex after Rocuronium Administration in Adult Surgical Patients [PDF]
The objective of this study was to determine the point after sugammadex administration at which sufficient or insufficient dose could be determined, using first twitch height of train-of-four (T1 height) or train-of-four ratio (TOFR) as indicators ...
Shigeaki Otomo +6 more
doaj +3 more sources
Sugammadex versus neostigmine after rocuronium continuous infusion in patients undergoing liver transplantation. [PDF]
Background: Rapid neuromuscular block reversal at the end of major abdominal surgery is recommended to avoid any postoperative residual block. To date, no study has evaluated sugammadex performance after rocuronium administration in patients undergoing ...
Cristian Deana +4 more
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Impact of Neostigmine and Sugammadex on Time to Leaving the Operating Room in a Community Hospital [PDF]
Purpose: The purpose of this study was to evaluate the impact of sugammadex on operating room (OR) times versus neostigmine in patients recovering from rocuronium or vecuronium induced neuromuscular blockade.
Julie St. John +7 more
openalex +3 more sources
Sugammadex is a direct reversal agent of aminosteroid muscle relaxants, particularly rocuronium, with promptly and completely reverse of deep neuromuscular block (NMB), which allows better surgical conditions. Sugammadex exhibits advantages over indirect
Hsiao-Cheng Chang +4 more
doaj +1 more source
Objective To conduct a meta-analysis to compare different dosing scalars of sugammadex in a morbidly obese population for reversal of neuromuscular blockade (NMB).
Jian-Qiang Liao +4 more
doaj +1 more source
Biological evaluation of the effect of sugammadex on hemostasis and bleeding [PDF]
BackgroundNotification of sugammadex has been supplemented with a section on hemostasis, including a longer clotting time in the first minutes following injection, without any documented clinical consequences.
Julien Raft +4 more
doaj +1 more source
Evaluation of the vasorelaxant effect of Sugammadex on the arterial smooth muscle in rats
Although NMBAs (Neuro Muscular Blocking Agents) have been used for a long time, postoperative residual curarization is still a significant problem. Nowadays, an agent named Sugammadex is used for the reversal of curarization.
Mustafa Karademir +2 more
doaj +1 more source
Sugammadex has been approved for reversal of neuromuscular blockade by vecuronium and rocuronium in adults undergoing surgery. Although widely used in the operating room, sugammadex has not been investigated in the intensive care unit setting. This study
Răzvan Bologheanu +5 more
doaj +1 more source
Anaphylactic shock after sugammadex administration, induced by formation of a sugammadex-rocuronium complex -a case report- [PDF]
Background Sugammadex is a reversal agent for non-depolarizing neuromuscular blockers and widely used worldwide on account of its rapid and effective reversal from neuromuscular blockade, despite its advantages, multiple cases of sugammadex-induced ...
Gunn Hee Kim +6 more
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