Results 11 to 20 of about 7,482 (199)

Effects of sugammadex on heart rate variability in anesthetized male rats

open access: yesPhysiological Reports
The administration of sugammadex has been associated with bradycardia and rarely asystole; however, the underlying mechanisms remain unclear. We examined heart rate variability (HRV) as an index of autonomic nervous system activity and investigated the ...
Mika Nishikawa   +4 more
doaj   +2 more sources

Appropriate dosing of sugammadex for reversal of rocuronium-/vecuronium-induced muscle relaxation in morbidly obese patients: a meta-analysis of randomized controlled trials

open access: yesJournal of International Medical Research, 2022
Objective To conduct a meta-analysis to compare different dosing scalars of sugammadex in a morbidly obese population for reversal of neuromuscular blockade (NMB).
Jian-Qiang Liao   +4 more
doaj   +1 more source

Biological evaluation of the effect of sugammadex on hemostasis and bleeding [PDF]

open access: yesKorean Journal of Anesthesiology, 2015
BackgroundNotification of sugammadex has been supplemented with a section on hemostasis, including a longer clotting time in the first minutes following injection, without any documented clinical consequences.
Julien Raft   +4 more
doaj   +1 more source

Evaluation of the vasorelaxant effect of Sugammadex on the arterial smooth muscle in rats

open access: yesMedicine Science, 2023
Although NMBAs (Neuro Muscular Blocking Agents) have been used for a long time, postoperative residual curarization is still a significant problem. Nowadays, an agent named Sugammadex is used for the reversal of curarization.
Mustafa Karademir   +2 more
doaj   +1 more source

A retrospective study of sugammadex for reversal of neuromuscular blockade induced by rocuronium in critically ill patients in the ICU

open access: yesScientific Reports, 2022
Sugammadex has been approved for reversal of neuromuscular blockade by vecuronium and rocuronium in adults undergoing surgery. Although widely used in the operating room, sugammadex has not been investigated in the intensive care unit setting. This study
Răzvan Bologheanu   +5 more
doaj   +1 more source

Anaphylactic shock after sugammadex administration, induced by formation of a sugammadex-rocuronium complex -a case report- [PDF]

open access: yesKorean Journal of Anesthesiology, 2019
Background Sugammadex is a reversal agent for non-depolarizing neuromuscular blockers and widely used worldwide on account of its rapid and effective reversal from neuromuscular blockade, despite its advantages, multiple cases of sugammadex-induced ...
Gunn Hee Kim   +6 more
doaj   +1 more source

Conventional reversal of rocuronium-induced neuromuscular blockade by sugammadex in Korean children: pharmacokinetics, efficacy, and safety analyses

open access: yesFrontiers in Pharmacology, 2023
Background: Sugammadex is known to reverse neuromuscular blockade induced by non-depolarizing agents. In children, the recommended dose for reversal of moderate neuromuscular blockade is 2 mg/kg.
Sang-Hwan Ji   +17 more
doaj   +1 more source

Advantages and pitfalls of clinical application of sugammadex [PDF]

open access: yesAnesthesia and Pain Medicine, 2020
Sugammadex, a modified γ-cyclodextrin, is one of the drugs focused on in the anesthetic field because it provides rapid and complete reversal from neuromuscular blockade (NMB) by encapsulating rocuronium.
Hyung Young Lee, Ki Tae Jung
doaj   +1 more source

Rocuronium-sugammadex use for electroconvulsive therapy in a hemodialysis patient: a case report

open access: yesJA Clinical Reports, 2016
Background Recently, rocuronium with subsequent use of sugammadex was proposed for electroconvulsive therapy (ECT) as an alternative to succinylcholine.
Shigeaki Kurita   +5 more
doaj   +1 more source

Reversal of rocuronium‐induced intense neuromuscular blockade by sugammadex in Korean children: A pharmacokinetic and pharmacodynamic analysis

open access: yesClinical and Translational Science, 2023
Sugammadex, a selective antagonist of steroidal non‐depolarizing neuromuscular blocking agents, has been used in children in limited circumstances. However, neither pharmacokinetics (PKs) nor recovery profile of sugammadex for intense neuromuscular ...
Sang‐Hwan Ji   +8 more
doaj   +1 more source

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