Results 41 to 50 of about 3,851 (159)

Sugammadex compared with Neostigmine/Glycopyrrolate: An Analysis of Total PACU Time, Responsiveness, and Potential for Economic Impact

INNOVATIONS in Pharmacy, 2019
Studies have previously shown sugammadex works faster and more effectively than neostigmine/glycopyrrolate at reversal of neuromuscular blockade by rocuronium and vecuronium.
Yoon Jung Lee, Kayla Leigh Money, Amber Elliott   +2 more
doaj   +1 more source

Sugammadex

Reactions Weekly, 2023
Manila Singh, Swati Chhabra
  +7 more sources

Is lower-dose sugammadex a cost-saving strategy for reversal of deep neuromuscular block? Facts and fiction

BMC Anesthesiology, 2018
Background Sugammadex, a γ-cyclodextrin derivative, belongs to a new class of selective relaxant binding agents. Sugammadex was approved 10-years ago by the European medicines agency and today is used in clinical anesthesia and emergency medicine ...
Hans D de Boer, Ricardo V Carlos, Sorin J Brull   +2 more
doaj   +1 more source

Myasthenia Gravis and Thymoma

Muscle &Nerve, EarlyView.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor, Lukas Delasos, Daniel P. Raymond, Erik Seroogy, Jason Lempel, Yuebing Li   +5 more
wiley   +1 more source

Error Traps in Pediatric Neuromuscular Block

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Neuromuscular blocking agents are essential for safe pediatric anesthesia but remain a frequent source of preventable morbidity when misused, inadequately monitored, or incompletely reversed. Children, particularly neonates and infants, are especially vulnerable to residual neuromuscular block due to developmental pharmacological ...
Gabriel Soares de Sousa, Debra Faulk, Vinicius Caldeira Quintao, Niekoo Abbasian, Hans D. de Boer, Ricardo Vieira Carlos   +5 more
wiley   +1 more source

Effects of sugammadex on heart rate variability in anesthetized male rats

Physiological Reports
The administration of sugammadex has been associated with bradycardia and rarely asystole; however, the underlying mechanisms remain unclear. We examined heart rate variability (HRV) as an index of autonomic nervous system activity and investigated the ...
Mika Nishikawa, Toru Kawada, Keita Saku, Hiroyuki Kinoshita, Shinji Kawahito   +4 more
doaj   +1 more source

Comparison of Different Neostigmine Doses for Reversal of Cisatracurium‐Induced Neuromuscular Block in Children Under Total Intravenous Anesthesia: A Randomized Controlled Trial

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Neostigmine is widely used to reverse nondepolarizing neuromuscular blockade in children, but the optimal dose under total intravenous anesthesia is uncertain. Aims The primary aim was to compare the time to full neuromuscular recovery (TOF ratio of 1.0) following administration of neostigmine at doses of 0, 10, 20, and 30 μg/kg in ...
Antonio J. M. M. Neto, Guilherme L. Benette, Letícia C. Siqueira, Marian M. Santos, Marco A. P. Costa, Rodrigo L. Alves, Eduardo T. Moro, Norma S. P. Módolo   +7 more
wiley   +1 more source

Association of Preoperative Inflammatory Markers With Preoperative Anxiety and Emergence Agitation in Children

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Emergence agitation (EA) is a postoperative neurobehavioral complication characterized by a transient disturbance in cognition and perception following anesthesia. Neuroinflammation is thought to play a central role in its pathophysiology.
Nezahat Merve Ata Soylu, Zehra Hatipoglu, Ersel Gulec, Mediha Turktan, Nurefsan Sadıkoglu, Yusuf Kemal Arslan, Dilek Ozcengiz   +6 more
wiley   +1 more source

Safer prehospital anaesthesia: updated guidelines from the Association of Anaesthetists

Anaesthesia, EarlyView.
Summary Introduction Prehospital emergency anaesthesia is recognised as a high‐risk clinical intervention. These updated guidelines consider changes in prehospital practice and parallel changes in the practice of in‐hospital emergency anaesthesia, with the aim of encouraging standardised safe anaesthetic practice in a challenging clinical area.
David Lockey, Celestine Weegenaar, Imran Ahmad, Pascale Avery, Philip Cowburn, Richard M. Lyon, Giles Nordmann, Andrew J. Pountney, Cosmo F. M. Scurr, Matthew D. Wiles   +9 more
wiley   +1 more source

Efficacy and safety of sugammadex in patients undergoing renal transplantation

JA Clinical Reports, 2018
Background Sugammadex reverses rocuronium by encapsulating it, creating a stable complex that is mainly excreted by the kidneys. Nonetheless, in view of exposure to sugammadex during renal transplantation, current safety data are insufficient.
Yasumasa Ono, Yoshihito Fujita, Takahiro Kajiura, Hazuki Okawa, Juntaro Nakashima, Hideo Isobe, Yoshihiro Fujiwara   +6 more
doaj   +1 more source