Results 51 to 60 of about 3,851 (159)

Knowledge and Understanding of the Safety and Efficacy Aspects of BRIDION® Among Canadian Anesthesiologists

Drugs - Real World Outcomes, 2020
Background BRIDION® (sugammadex sodium) is an agent for the reversal of neuromuscular blockade (NMB) induced by rocuronium and vecuronium in general anesthesia.
Annette Stemhagen, Parambir Bhangu, Wenjun Zhong, Michele Julian, Gretty Deutsch, Carol Koro   +5 more
doaj   +1 more source

Sugammadex vs. neostigmine and the risk of postoperative pulmonary complications after upper gastrointestinal endoscopic procedures: a propensity score matched analysis of 15,730 patients

Anaesthesia, EarlyView.
Summary Introduction Postoperative pulmonary complications after upper gastrointestinal endoscopic procedures under general anaesthesia are clinically important and may be exacerbated by residual neuromuscular block. We evaluated whether antagonism of neuromuscular block with sugammadex rather than neostigmine is associated with improved respiratory ...
Yung‐Fong Tsai, Kuo‐Chuan Hung, Chih‐Yi Hsu, Huan‐Tang Lin, Yi‐Chen Lai, Shao‐Chun Wu   +5 more
wiley   +1 more source

Required dose of sugammadex or neostigmine for reversal of vecuronium‐induced shallow residual neuromuscular block at a train‐of‐four ratio of 0.3

Clinical and Translational Science, 2022
Residual shallow neuromuscular block (NMB) is potentially harmful and contributes to critical respiratory events. Evidence for the optimal dose of sugammadex required to reverse vecuronium‐induced shallow NMB is scarce. The aims of the present study were
Jing He, Huan He, Xing Li, Mei Sun, Zhihao Lai, Bo Xu   +5 more
doaj   +1 more source

Sugammadex-induced anaphylactic reaction: A systematic review

Journal of Anaesthesiology Clinical Pharmacology, 2022
Perioperative anaphylaxis is a rare, but life-threatening hypersensitivity reaction for patients undergoing surgical procedures. Sugammadex is a relatively new drug used to reverse the neuromuscular blockade of specific anesthetics in surgery.
Fatih Zecic, Mary H Smart, Taylor C Abbey, Alex Pazhempallil, Colin Korban   +4 more
doaj   +1 more source

Remifentanil Versus Rocuronium for Optimising Video Laryngoscopy Assisted Tracheal Intubation—The ROCVIDEO Trial Protocol

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background Routine use of neuromuscular blocking agents (NMBAs) is widely recommended to facilitate tracheal intubation. However, NMBA use is associated with potential adverse effects, including postoperative respiratory complications, intraoperative awareness and anaphylaxis.
Emil Ørskov Ipsen, Lars Hyldborg Lundstrøm, Åse Lodenius, Gustav Fisker, Magnus Fuhr Hovind, Christian Lindgren Nielsen, Hrund Oskarsdottir, Camilla Strøm, Charlotte Vallentin Rosenstock, Karl Peter Damgård Madsen, Sine Wichmann, Arash Afshari, Jacob Hessel Andersen, Helene Korvenius Nedergaard, Louise Bill, Maria Cronhjort, Ole Mathiesen, Janus Christian Jakobsen, Matias Vested, Anders Kehlet Nørskov   +19 more
wiley   +1 more source

Pharmacokinetics of Sugammadex Dosed by Actual and Ideal Body Weight in Patients With Morbid Obesity Undergoing Surgery

Clinical and Translational Science, 2021
This analysis of a published study (NCT03346070) evaluated the pharmacokinetics (PKs) of sugammadex dosed by actual body weight (ABW) or ideal body weight (IBW) for reversal of moderate or deep neuromuscular block (M‐NMB or D‐NMB) in adults with morbid ...
Kate Mostoller, Rebecca Wrishko, Lata Maganti, W. Joseph Herring, Mariëlle vanZutphen‐van Geffen   +4 more
doaj   +1 more source

Advantages of Alkali Metal Adduct Formation in Cyclic Ion Mobility‐Mass Spectrometry of O‐Methylated Cyclodextrin Isomers—Separation and Crossring Fragmentation

Chemistry–Methods, Volume 6, Issue 6, June 2026.
Cyclic ion mobility–tandem mass spectrometry (cIM‐MS/MS) enables rapid differentiation of O‐methylated cyclodextrin (MeCD) regioisomers. The method separates 2,3‐ and 2,6‐DIMEB (heptakis‐2,3‐ and ‐2,6‐di‐O‐methyl‐β‐cyclodextrins) and identifies them via characteristic crossring fragmentation.
Péter Soma Szakály, Arnold Steckel, Dávid Papp, Erzsébet Varga, Gitta Schlosser   +4 more
wiley   +1 more source

Risk of bronchospasm and coronary arteriospasm with sugammadex use: a post marketing analysis

Therapeutic Advances in Drug Safety, 2019
Introduction: Sugammadex is used for the reversal of neuromuscular blockade caused by rocuronium bromide and vecuronium bromide. As part of the post licensing phase of drug development, adverse events related to the use of sugammadex are still being ...
Pushkar Aggarwal
doaj   +1 more source

Staggering the dose of sugammadex lowers risks for severe emergence cough: a randomized control trial

BMC Anesthesiology, 2017
Background Cough on emergence has been reported as a common adverse reaction with sugammadex reversal. We investigated if staggering the dose of sugammadex will reduce emergence cough in a single-center, randomized, double-blinded study.
Loh P.S., M.M. Miskan, Chin Y.Z., R.A. Zaki   +3 more
doaj   +1 more source

Sugammadex for reversal of neuromuscular blockade: a retrospective analysis of clinical outcomes and cost-effectiveness in a single center

ClinicoEconomics and Outcomes Research, 2016
Michele Carron, Fabio Baratto, Francesco Zarantonello, Carlo Ori Department of Medicine, Anesthesiology and Intensive Care, University of Padova, Padova, Italy Objective: The aim of the study is to evaluate the clinical and economic impact of introducing
Carron M, Baratto F, Zarantonello F, Ori C   +3 more
doaj