Results 71 to 80 of about 3,851 (159)

The arousal effect of sugammadex reversal of neuromuscular blockade differs with anesthetic depth in propofol-remifentanil anesthesia: a randomized controlled trial

Scientific Reports, 2023
Sugammadex reverses neuromuscular blockade by encapsulating steroidal neuromuscular blockers; therefore, it does not pharmacologically affect sedation levels.
Jeayoun Kim, Jie Ae Kim, Jae Ni Jang, Mikyung Yang, Hyun Joo Ahn, Jiwon Choi, Sungwoo Jo   +6 more
doaj   +1 more source

Cyclodextrin‐Amino Acid Conjugates: Synthesis and Pharmaceutical Applications

ChemistryEurope, Volume 4, Issue 4, April 2026.
Cyclodextrins (CDs) can be combined with amino acids via host‐guest complexation or by covalent conjugation through various synthetic routes. The chemical modifications introduce structural versatility, multifunctionality, and biocompatibility, which are essential characteristics for designing effective, next‐generation pharmaceutical formulations ...
Andrea Cesari, Nicola Lomuscio, Fabio Bellina   +2 more
wiley   +1 more source

Respiratory muscle activity after spontaneous, neostigmine- or sugammadex-enhanced recovery of neuromuscular blockade: a double blind prospective randomized controlled trial

BMC Anesthesiology, 2019
Background The use of neostigmine after neuromuscular blockade (NMB) has been associated with postoperative respiratory complications. In previous studies, we found lower diaphragmatic activity after neostigmine reversal of NMB, compared to sugammadex ...
Tom Schepens, Koen Janssens, Sabine Maes, Davina Wildemeersch, Jurryt Vellinga, Philippe G. Jorens, Vera Saldien   +6 more
doaj   +1 more source

Neuromuscular Block and Video Laryngoscope to Facilitate Intubation—A Survey of Current Practice in Denmark and Sweden

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 4, April 2026.
ABSTRACT Background Neuromuscular blocking agents (NMBA) provide optimal conditions for tracheal intubation. A high dose of opioid can be used as an alternative but may give suboptimal conditions for intubation. The use of a video laryngoscope for intubation might eliminate this potential difference.
Åse Lodenius, Louise Holland‐Bill, Emil Ørskov Ipsen, Maria Cronhjort, Arash Afshari, Matias Vested, Andreas Creutzburg, Lars Hyldborg Lundstrøm, Helene Korvenius Nedergaard, Anders Kehlet Nørskov, ROCVIDEO Survey Collaborator Group, Mette Schytt Price, Christian Jessen, Mathias Sinkbæk Thomsen, Mikkel Schjødt Heide Jensen, Torben Krabbe Laustrup, Karina Baekby Houborg, Fabian Spies, Line Agger Kolstrup, Anni Nørgaard Jeppesen, Hanna Poulsen, Jannie Bisgaard, Hansjörg Selter, Cecilie Harries Klementsen, Hayan El‐Hallak, Daniel Hägi‐Pedersen, Jakob Hessel Andersen, Anders Lolle, Jacqueline Møller Mistry, Peter Martin Hansen, Kirsten Lerche Licht, Wojciech Jan Pietrzyk, Michael Leth Jørgensen, Christina Borgen, Anders Karlsen, Karsten Kindberg, Kim Wildgaard, Laila Mulla Reich, Simon Strøyer, Robin Lohse, Mette Lea Mortensen, Rune Lundsgaard, Mark Søgaard Niegsch, Erik Wikström, Anna Bandert, Carl Olsson, Malin Bohlin, Mälarsjukhuset Eskilstuna, Nanny Hareide, Olof Brattström, Karin Bursell, Lars Mattsson, Pontus Weinar, Katrin Ögren, Åsa Eriksson Nordesjö, Björn Ahlström, Petter Huitfeldt, Jakob Boethius, Tomi Myrberg, Jakob Walldén, Ulf A. Karlsson, Simon Näverlo, Jonas Rudenstam, Sofia Hannu, Pauline Koch, Thorey Steinarsdóttir, Gustaf Rosin, Anna Borglund Hemph, Jacob Broms, Liselott Wickerts, Anna Wennmo, Hanna Smeds, Mark Larsson, Jelena Paegle, Jonas Graf, Pierre Sundin, Katalin Rockstroh, Sebastian Felixson, Jim Runesson, Johan Berkius, Helena Krook, Louise Walther Sturesson, Fredrik Sjövall, Nikolaus Groll, Olof Nilsson, Johanna Broman, Susanne Gustafsson Liljenthal, Isabella Görloff Nordenskjöld, Martina Jarnlo Klarén, Andreas Ekman   +89 more
wiley   +1 more source

Prediction of Optimal Reversal Dose of Sugammadex after Rocuronium Administration in Adult Surgical Patients

Anesthesiology Research and Practice, 2014
The objective of this study was to determine the point after sugammadex administration at which sufficient or insufficient dose could be determined, using first twitch height of train-of-four (T1 height) or train-of-four ratio (TOFR) as indicators ...
Shigeaki Otomo, Hajime Iwasaki, Kenichi Takahoko, Yoshiko Onodera, Tomoki Sasakawa, Takayuki Kunisawa, Hiroshi Iwasaki   +6 more
doaj   +1 more source

Economic analysis of sugammadex versus neostigmine for reversal of neuromuscular blockade for laparoscopic surgery in China

Health Economics Review, 2020
Background Neuromuscular blockade and pneumoperitoneum (PP) are important factors to ensure successful laparoscopic surgery. However, residual neuromuscular blockade (rNMB) and PP are associated with many unfavorable complications.
Maodong Ren, Ying Wang, Yan Luo, Jia Fang, Yongji Lu, Jianwei Xuan   +5 more
doaj   +1 more source

Consensus on the Management of Anesthetic Agents During Digestive Motility Measurements and Proposal of a Standardized Protocol for Anesthesia (French Neuro Gastroenterology Group GFNG and Committee of Anesthetic French Experts)

Neurogastroenterology &Motility, Volume 38, Issue 4, April 2026.
Anesthesia can alter measurements during digestive endoscopies, yet no standardized protocol currently exists. Two expert groups—the French Neuro‐Gastroenterology Group (GFNG) and anesthesiologists—used the Delphi method to reach a consensus on which drugs have an influence (91 amendments), ultimately resulting in a proposed anesthesia protocol (28 ...
Domitille Renard, Thomas Clavier, Osama Abou‐Arab, Gérard Amarenco, Emmanuel Besnier, Alice Blet, Matthieu Boisson, Charlène Brochard, Benoit Coffin, Audrey De Jong, Denis Frasca, Marc Garnier, Aurelie Gouel, Jérémie Jacques, Arthur James, Yoann Launey, Anne‐Marie Leroi, Chloé Melchior, Daphné Michelet, François Mion, Maxime Nguyen, Emmanuel Rineau, Amélie Rollé, Sabine Roman, Stéphanie Sigaut, Heithem Soliman, Fabien Wuestenberghs, Frank Zerbib, Guillaume Gourcerol, Charlotte Desprez   +29 more
wiley   +1 more source

Half dose sugammadex combined with neostigmine is non-inferior to full dose sugammadex for reversal of rocuronium-induced deep neuromuscular blockade: a cost-saving strategy

BMC Anesthesiology, 2017
Background Sugammadex reverses the effect of rocuronium more rapidly and effectively than neostigmine, at all levels of neuromuscular blockade (NMB). However, its cost is prohibitive.
Marie T. Aouad, Waseem S. Alfahel, Roland N. Kaddoum, Sahar M. Siddik-Sayyid   +3 more
doaj   +1 more source

Effect of the rs7858836 Single‐Nucleotide Polymorphisms of the ASTN2 Gene on Pain‐Related Phenotypes in Japanese Women Who Underwent Laparoscopic Gynecologic Surgery

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
Schematic overview of the study examining the association between the ASTN2 rs7858836 T allele and postoperative pain–related phenotypes in humans. The analysis focuses on the relationship between this genetic variant and postoperative pain intensity as well as analgesic responses.
Rie Inoue, Daisuke Nishizawa, Shoko Okahara, Atsuko Hara, Hisako Okada, Junko Hasegawa, Yuko Ebata, Kyoko Nakayama, Masakazu Hayashida, Kazutaka Ikeda   +9 more
wiley   +1 more source

Use of sugammadex in patients with neuromuscular disorders: a systematic review of case reports

BMC Anesthesiology, 2019
Background Sugammadex is a modified gamma-cyclodextrin that acts by selectively encapsulating free amino-steroidal neuromuscular relaxants. Several case reports have been published on the use of sugammadex in patients with neuromuscular disorders that ...
Usha Gurunathan, Shakeel Meeran Kunju, Lisa May Lin Stanton   +2 more
doaj   +1 more source