Results 101 to 110 of about 10,440 (199)

Diazirines Beyond Photoaffinity Labeling: A Comprehensive Overview of Applications in Biological Sciences, Materials Chemistry, and NMR‐Spectroscopy

open access: yesAngewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Diazirines are three‐membered, nitrogen‐containing heterocycles that decompose under light or heat to generate carbenes. For the past two decades, they have served mainly as minimally invasive tags in photoaffinity labeling (PAL). More recently, their value as versatile carbene precursors has been recognized.
Dominik Schnalzer   +4 more
wiley   +2 more sources

Recent Progressions in Applications of Bioactive Polysaccharides in Food and Health Sciences: A Comprehensive Review

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Polysaccharides play a pivotal role in the development of safe and healthy foods. They ameliorate fatigue, preserve the microflora of the gastrointestinal tract, and provide health for the gut in living organisms. These biopolymers are applied for the fabrication of breakthrough drug delivery systems and potential platforms in regenerative medicine ...
M V N L Chaitanya   +14 more
wiley   +1 more source

Genetic variants underlying precancerous conditions of hepatocellular carcinoma

open access: yesInternational Journal of Cancer, Volume 158, Issue 3, Page 488-502, 1 February 2026.
Abstract Hepatocellular carcinoma (HCC) is the most common form of liver cancer, accounting for 80% of cases worldwide. While chronic hepatitis B and C infections remain primary risk factors, emerging evidence highlights the increasing contributions of metabolic dysfunction‐associated steatotic liver disease (MASLD) and alcohol‐associated liver disease
Jonathan Jaime G. Guerrero   +7 more
wiley   +1 more source

Carboxydotrophic Acetogenesis in Alkaline Conditions Results in Transient Formate Production by the Halo‐Alkaliphilic Acetogen Haloacetibacter carboxydivorans Gen. Nov. sp. Nov

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
This work presents the physiological exploration of the halo‐alkaliphilic, carboxydotrophic acetogen bacterium MD4. In contrast to well‐characterised neutrophilic and slightly acidophilic acetogenic carboxydotrophs, this work shows an important role for formate production, instead of ethanol, as a redox exhaust mechanism in alkaline conditions ...
Martijn Diender   +5 more
wiley   +1 more source

The Role of the Gut Microbiome in the Complex Network of Frailty Syndrome and Associated Comorbidities in Aging

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá   +5 more
wiley   +1 more source

Draft genome and alcohol dehydrogenase dataset of thermoanaerobacter uzonensis bacterium strain AK85. [PDF]

open access: yesData Brief
Abraham CA   +6 more
europepmc   +1 more source

Lifespan‐Extending Endogenous Metabolites

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

The Natural Redox Cofactor Pyrroloquinoline Quinone (PQQ) Enables Photocatalytic Radical Cyclizations. [PDF]

open access: yesAngew Chem Int Ed Engl
Bahukhandi SB   +8 more
europepmc   +1 more source

The influence of rising carbon dioxide on maize development: genotypic differences in growth, lignification and folate pathway

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 2, Page 1283-1298, 30 January 2026.
Abstract BACKGROUND Rising atmospheric carbon dioxide (CO2) is a key driver of climate change, making it essential to understand its effects on crop growth and metabolism. This study examines maize C01 (inbred) and B73 (mutant), under elevated CO2 (600, 1200 and 1800 ppm) at three growth stages [40, 70 and 90 days after sowing (DAS)].
Pirzada Khan   +5 more
wiley   +1 more source

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