Results 61 to 70 of about 3,546,127 (337)

Nucleotide-sugar metabolism in plants: the legacy of Luis F. Leloir.

open access: yesJournal of Experimental Botany, 2021
This review commemorates the 50th anniversary of the Nobel Prize in Chemistry awarded to Luis F. Leloir 'for his discovery of sugar-nucleotides and their role in the biosynthesis of carbohydrates'. He and his co-workers discovered that activated forms of
C. Figueroa, J. Lunn, A. Iglesias
semanticscholar   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Genetic Structure Analysis in Sugarcane (Saccharumspp.) Using Target Region Amplification Polymorphism (TRAP) Markers Based on Sugar- and Lignin-Related Genes and Potential Application in Core Collection Development

open access: yes, 2020
Sugarcane is a main bioenergy crop and is highlighted worldwide in sugar, ethanol, and biomass production. Sugar and lignin contents are important quality traits for traditional and energy cane cultivar development, respectively.
Manechini, Joao Ricardo Vieira [UNESP]   +6 more
core   +1 more source

From acidity to sweetness: a comprehensive review of carbon accumulation in grape berries

open access: yesMolecular Horticulture
Most of the carbon found in fruits at harvest is imported by the phloem. Imported carbon provide the material needed for the accumulation of sugars, organic acids, secondary compounds, in addition to the material needed for the synthesis of cell walls ...
Lizhen Lu, Serge Delrot, Zhenchang Liang
doaj   +1 more source

Insulin resistance, does it exist? The current state of knowledge

open access: yesJournal of Education, Health and Sport, 2023
Insulin resistance is a growing concern worldwide, affecting millions of people and increasing the risk of various metabolic disorders, including type 2 diabetes, cardiovascular diseases, and fatty liver disease.
Milena Michalska   +8 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Significantly regulated genes involved in ‘amino sugar and nucleotide sugar metabolism’ under calcium lactate stress.

open access: yes, 2015
Significantly regulated genes involved in ‘amino sugar and nucleotide sugar metabolism’ under calcium lactate stress.
Jiayang Qin (223975)   +6 more
core   +1 more source

Regulation of fructan metabolism in barley leaves [PDF]

open access: yes, 2004
Fructans, the polymers of fructose (Fru), are major non-structural storage carbohydrates in the vegetative tissues of many higher plants including temperate forage grasses and cereals, as well as major crop plants such as wheat and barley.
Nagaraj, Vinay Janthakahalli
core   +1 more source

Advances in Engineering Nucleotide Sugar Metabolism for Natural Product Glycosylation in Saccharomyces cerevisiae

open access: yesACS Synthetic Biology
Glycosylation is a ubiquitous modification present across all of biology, affecting many things such as physicochemical properties, cellular recognition, subcellular localization, and immunogenicity.
Samantha A Crowe   +4 more
semanticscholar   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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