Results 201 to 210 of about 54,607 (298)

Synthesis of siRNAs containing carbocyclic nucleotides and the role of cyclopentane conformation in RNAi activity. [PDF]

RSC Chem Biol
Kundu J, Datta D, Akabane-Nakata M, Mandal S, Krampert M, Egli M, Manoharan M.   +6 more
europepmc   +1 more source

Chemical Routes to Primitive Membranes: Prebiotic Lipid Formation at the Origin of Life. [PDF]

Life (Basel)
Shvetsova A, Fiore M.
europepmc   +1 more source

Trehalose 6-phosphate makes sugar sense

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2008
Primavesi, L. F., Jhurreea, D., Zhang, Y., Andralojc, P. J., Wingler, A., Paul, M. J.   +5 more
openaire   +1 more source

Cell Suspension of the Tree Fern <i>Cyathea smithii</i> (J.D. Hooker) and Its Metabolic Potential During Cell Growth: Preliminary Studies. [PDF]

Int J Mol Sci
Rybczyński JJ, Marczak Ł, Skórkowska-Telichowska K, Stobiecki M, Szopa J, Mikuła A.   +5 more
europepmc   +1 more source

A Synergistic Inhibitor Development Strategy Against Human UDP‐Galactose‐4‐Epimerase

Angewandte Chemie International Edition, EarlyView.
The epimerase GalE is crucial for the biosynthesis of cancer‐relevant O‐GalNAc glycans. Here, we employ orthogonal, structurally enabled small molecule fragment screens to yield both covalent and non‐covalent inhibitors against GalE within no more than 22 elaborated compounds.
William M. Browne, Jonathan Pettinger, Teresa Weckwerth, Andrew Purkiss, Sing Hei Lok, Louisa Penicaut, Roksana Ogrodowicz, Raveena Prema, Simone Kunzelmann, Chloe Roustan, Ganka Bineva‐Todd, Saskia Pieters, Francesca Zappacosta, Alfred E. Doherty, Isobel Oram, Christelle Soudy, Robert Quinlan, Joanna Redmond, Svend Kjaer, David House, Stephane Mouilleron, Jacob T. Bush, Benjamin Schumann   +22 more
wiley   +1 more source

Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells. [PDF]

Nat Chem Biol
Li Z, Chawla H, Di Vagno L, Ní Cheallaigh A, Critcher M, Sammon D, Gonzalez-Rodriguez E, Briggs DC, Chung N, Chang V, Mahoney KE, Cioce A, Bineva-Todd G, Wang PY, Liu YC, Murphy LD, Chen YH, Narimatsu Y, Miller RL, Willems LI, Malaker SA, Huang ML, Miller GJ, Hohenester E, Schumann B.   +24 more
europepmc   +1 more source

COPPER-PHOSPHATE MIXTURES AS SUGAR REAGENTS

Journal of Biological Chemistry, 1918
Otto Folin, W.S. McEllroy
openaire   +1 more source

Incorporation of Novel Synthetic Glycolipids in Liposomal Nanoparticles Affects Opsonization and In Vivo Clearance

Angewandte Chemie International Edition, EarlyView.
We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu, Xuehan Li, Yu Gao, Shijia Tao, Xiaofei Li, Lemei Zhao, Wenshuai Han, Hao Fan, Ying Qiu, Man Wang, Luying Zhou, Xiaoyan Fang, Wenhua Yang, Haiyang Zhang, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang, Xiangzhao Mao   +18 more
wiley   +1 more source

Engineering of <i>Escherichia coli</i> for D-tagatose production from lactose and whey permeate via the tagatose-6-phosphate pathway. [PDF]

Curr Res Food Sci
Abzach A, Ben-Adiva R, Gruzdev N, Musa S, Yadid I.   +4 more
europepmc   +1 more source

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

Angewandte Chemie International Edition, EarlyView.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl, Claudia Höbartner   +1 more
wiley   +1 more source