Results 91 to 100 of about 1,000,995 (356)

Mediating Effects of Positive Thinking and Social Support on Suicide Resilience [PDF]

, 2018
Suicide has been the second leading cause of death for 18- to 24-year-olds in the United States since 2011. The stress experienced by undergraduate college students has the potential to increase one’s risk for suicide.
Bekhet, Abir K., Garnier-Villarreal, Mauricio, Matel-Anderson, Denise M.   +2 more
core   +1 more source

Why are so many Nepali women killing themselves? A review of key issues [PDF]

, 2015
Background: For decades the maternal mortality in Nepal was the lead cause of death among women, with great improvements in the maternal mortality ratio in the twentieth century the second most common cause has become more prominent.
Dhungel, A., Fanning, C., Marahatta, S. B., Simkhada, Padam, van Teijlingen, Edwin, Winter, R. C.   +5 more
core   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Moderating role of alcohol tolerance in the association between excessive drinking and psychological distress: a cross-sectional study among agricultural workers in Japan

BMC Public Health
Background Excessive drinking is a known risk factor for psychological distress; however, the role of alcohol tolerance in this relationship remains unclear.
Syohei Miyamoto, Fumiya Tanji, Suguru Iwano, Atushi Iwasawa, Hidenobu Ohta, Kyoichi Ono   +5 more
doaj   +1 more source

Long-term risk factors for suicide in suicide attempters examined at a medical emergency in patient unit: results from a 32-year follow-up study [PDF]

, 2020
Sara Probert-Lindström, Jonas Berge, Åsa Westrin, Agneta Öjehagen, Katarina Skogman Pavulans   +4 more
openalex   +1 more source

Changes in the pattern of suicides and suicide attempt admissions in relation to the COVID-19 pandemic [PDF]

, 2022
Christine Reif-Leonhard, Dorothea Lemke, Franziska Holz, Kira F. Ahrens, Christoph Fehr, Markus Steffens, Michael Grube, Christine M. Freitag, Sarah C. Kölzer, Sabine Schlitt, Rebekka Gebhardt, Theresa Gädeke, Helga Schmidt, Ferdinand M. Gerlach, Kira Wolff, Michael Stäblein, Nora Hauschild, Inga Beig, Louisa Wagner, Juliane Müller, Marcel A. Verhoff, Christiane Schlang, Andreas Reif   +22 more
openalex   +1 more source

A Comparative Examination of Suicide Rates among Hetero- & Homosexual Adolescents and Young Adults [PDF]

, 2012
The focus of this literature review will be on the comparison of suicide rates between heterosexual and homosexual adolescents and young adults (ages 14-24), and the possible contributing factors.
Schaaff, Arianna
core   +1 more source

Targeting the Dynamics Between TAMs and CAR‐T Cells in Solid Tumor Therapies

Advanced Science, EarlyView.
This review highlights the critical role of tumor‐associated macrophages (TAMs) in affecting CAR‐T cell therapy effectiveness in solid tumors. TAMs contribute to immune suppression through cytokine secretion, immune checkpoint activation, and metabolic reprogramming, leading to CAR‐T cell exhaustion and reduced efficacy. The article explores strategies
Xiang Zhang, Hao Zheng, Zi‐Chang Liu, Ling‐Jie Luo, Xiao Dong, Xin‐Gang Cui, Yan‐Wei Wu, Liang Chen   +7 more
wiley   +1 more source

Tackling social disconnection: an umbrella review of RCT-based interventions targeting social isolation and loneliness

BMC Public Health
Background Social isolation and loneliness are urgent public health concerns associated with negative physical and mental health outcomes. Understanding effective remedies is crucial in addressing these problems.
Thomas Hansen, Ragnhild Bang Nes, Kamila Hynek, Thomas Sevenius Nilsen, Anne Reneflot, Kim Stene-Larsen, Ragnhild Agathe Tornes, Julia Bidonde   +7 more
doaj   +1 more source

The impact of borderline personality disorder and sub-threshold borderline personality disorder on the course of self-reported and clinician-rated depression in self-harming adolescents

Borderline Personality Disorder and Emotion Dysregulation, 2017
Background Studies on adults suggest that the presence of comorbid depression and Borderline Personality Disorder (BPD) is associated with an elevated risk of self-harming behaviours and that self-harming behaviours, when present, will have higher ...
Ruth-Kari Ramleth, Berit Groholt, Lien M. Diep, Fredrik A. Walby, Lars Mehlum   +4 more
doaj   +1 more source