Results 111 to 120 of about 405,279 (308)
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Injury EpidemiologyBackground Rates of suicide remain elevated among U.S. Veterans and have increased disproportionately among Asian American and Pacific Islander (AAPI) Veterans.
Evan R. Polzer +6 more
doaj +1 more source
MedicinaBackground and Objectives: The impact of coronavirus disease 2019 (COVID-19) goes beyond the consequences of the infectious disease, especially as the measures taken to prevent the spread of the virus have had a very profound impact on people’s social ...
Vita Poštuvan +5 more
doaj +1 more source
The HSE Resource Officers for Suicide Prevention (ROSP) Learning Community of Practice (LCOP) agreed to establish a Social Media Sub-Group in response to the growing concern among ROSPs of social media posting and reporting of suspected suicides around
Social Media Sub-Group of the HSE Resource Officers for Suicide Prevention (ROSPs) Learning Community of Practice.
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HSE National Office for Suicide Pevention annual report 2013
, 2014 Annual report published by the HSE National Office for Suicide Prevention (NOSP), summarising its programme of work, expenditure, and details of funded services and initiatives from over 20 NGOs working in mental health and suicide ...
HSE National Office for Suicide Prevention (NOSP)
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British Journal of Clinical Pharmacology, EarlyView.Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari +2 more
wiley +1 more source
Exploring new avenues: Psychedelic‐assisted therapy for young people
British Journal of Clinical Pharmacology, EarlyView.Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou +3 more
wiley +1 more source
Borderline Personality Disorder and Emotion DysregulationBackground Emotion dysregulation is a transdiagnostic construct associated with mental health problems, including self-harm and borderline personality disorder (BPD).
Iselin Solerød Dibaj +2 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley +3 more
wiley +1 more source