Results 71 to 80 of about 83,910 (267)

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Brief, pragmatic measure of emotion dysregulation in young people – a preliminary validation of the BER-5

Borderline Personality Disorder and Emotion Dysregulation
Background Emotion dysregulation is a transdiagnostic construct associated with mental health problems, including self-harm and borderline personality disorder (BPD).
Iselin Solerød Dibaj, Sudan Prasad Neupane, Lars Mehlum   +2 more
doaj   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source

Experiences of Prisoners Living With Mental Health Conditions and Seeking or Receiving Mental Health Support in Prisons: An Integrative Review

Criminal Behaviour and Mental Health, EarlyView.
ABSTRACT Background Prisoners experience poor mental health and well‐being in prison, including severe mental illnesses. However, access to mental health support and treatment in prison is limited. We conducted an integrative review to synthesise prisoners' experiences of living with mental ill health and/or seeking or receiving mental health support ...
Anne Kairu, Judith Dyson, Damian Breen, James Skinner, Manuela Jarrett, Joanne Brooke   +5 more
wiley   +1 more source

Copula‐based joint modelling of emergency department visits with time‐varying dependence

Canadian Journal of Statistics, EarlyView.
Abstract Jointly modelling multiple correlated count time series is essential in health services research, where outcomes like emergency visits for mental health and substance use often evolve together. Ignoring these dependencies can obscure meaningful trends and limit the effectiveness of policy evaluation.
Guanjie Lyu, Cindy Feng, Lihui Liu
wiley   +1 more source

Prescription Sequence Symmetry Analysis of Glucagon‐Like Peptide‐1 Receptor Agonists and Neuropsychiatric Conditions

Clinical Pharmacology &Therapeutics, EarlyView.
Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are increasingly prescribed for type 2 diabetes and weight management. However, conflicting evidence from preclinical, clinical, and pharmacovigilance studies suggests potential neuropsychiatric effects.
Maria J. Alfonso Arvez, Sam Wade, Darshna Goordeen, Jenni Ilomäki, Amanda J. Cross, Monica Langiu, George S. Q. Tan   +6 more
wiley   +1 more source

Reward Processing in Binge Eating and Harmful Drinking: A Systematic Review

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Binge eating and harmful drinking commonly co‐occur, which worsens the physical and psychological consequences associated with either behavior alone. Reward processing alterations have been demonstrated among individuals who engage in binge eating or harmful drinking alone; however, there is limited understanding of how different ...
Taylor N. Breddy, Kendall M. Schmidt, Lindsay P. Bodell   +2 more
wiley   +1 more source

Therapist‐Guided Smartphone‐Based Aftercare for Inpatients With Severe Anorexia Nervosa (SMART‐AN): A Randomized Clinical Trial

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To evaluate the efficacy of a 16‐week therapist‐guided, smartphone‐based aftercare intervention as an add‐on to treatment as usual (TAU) following inpatient treatment for anorexia nervosa (AN). Method In this single‐center randomized clinical trial, 186 female inpatients with DSM‐5 AN (≥ 13 years; body mass index (BMI) ≥ 15.0 kg/m2 ...
Sandra Schlegl, Andreas Gerich, Yannik Terhorst, Christina Fricke Neumayr, Ulrich Voderholzer   +4 more
wiley   +1 more source

The use of social media after bereavement by suicide: results from a French online survey

BMC Psychiatry
Background According to recent research, the Internet and social media are shaping and changing how we die and mourn. However, the use of social media after bereavement by suicide remains poorly understood.
Edouard Leaune, Héloïse Rouzé, Laurène Lestienne, Kushtrim Bislimi, Margot Morgiève, Benoit Chalancon, Pauline Lau-Taï, Guillaume Vaiva, Pierre Grandgenèvre, Julie Haesebaert, Emmanuel Poulet   +10 more
doaj   +1 more source

Longitudinal Residential Eating Disorder Treatment Outcomes for Binge‐Eating Disorder When Using the Unified Treatment Model

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Despite its prevalence, research on binge‐eating disorder (BED) outcomes for residential treatment remains limited. To address this research scarcity, we evaluated changes in ED behaviors and comorbid symptoms, including depression and anxiety, for patients with BED that received residential eating disorder (ED) care from a ...
Kiki M. Kline, Briana Delibashi, Gayle Brooks, Shelby N. Ortiz   +3 more
wiley   +1 more source