Results 51 to 60 of about 320,187 (315)

Risk factors for suicidal ideation among survivors of suicide loss using a psychological support hotline

Frontiers in Psychiatry
IntroductionSuicide of a loved one significantly affects the physical and mental well-being of close friends and family members, potentially escalating to suicidal ideation in severe cases.
Hong Liang, Hong Liang, Zikang Liu, Zikang Liu, Zikang Liu, Xingxue Li, Xingxue Li, Xingxue Li, Jing An, Jing An, Liting Zhao, Liting Zhao, Lin Chen   +12 more
doaj   +1 more source

Evaluation of the factor structure of the Russian version of PID-5-BF

European Psychiatry, 2022
Introduction Traditional categorical classifications of personality disorders (PD) have been criticized for insufficient structural and cross-cultural validity.
M. Zinchuk, G. Kustov, A. Gersamija, A. Yakovlev, E. Pashnin, N. Voinova, S. Popova, A. Guekht   +7 more
doaj   +1 more source

Suizidprävention: Vorgehensweisen und Wirksamkeit [PDF]

, 2005
According to official statistics every year 11,000 persons in Germany die from suicide. 20 years ago nearly 19,000 suicides were registered. What are the causes for this decrease?
Althaus D, Bagley C, Birmingham PK, David Althaus, De Leo D, Evans MO, Gunnell D, Hafner H, Hawton K, Jennings C, Kreitmann N, Lewis G, Meltzer HY, Morgan HG, Motto JA, Phillips DP, Salkovskis PM, Schmidtke A, Shearin EN, Ziegler W   +19 more
core   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Links Between Social Support, Thwarted Belongingness, and Suicide Ideation among Lesbian, Gay, and Bisexual College Students [PDF]

, 2017
Emerging adults with a lesbian, gay, or bisexual (LGB) identity are at greater risk for engaging in suicide-related behaviors. This disparity highlights a need to elucidate specific risk and protective factors associated with suicide-related behaviors ...
Hill, Ryan M, Kaplow, Julie B, Mooney, Megan A, Rooney, Evan E   +3 more
core   +1 more source

"Talk" about male suicide? Learning from community programmes [PDF]

, 2013
Purpose – The purpose of this paper is to examine the contribution of public awareness campaigning in developing community capacity toward preventing male suicide and explores emerging considerations for suicide prevention programme development.
Braybrook, D, Robertson, S, Robinson, M
core   +2 more sources

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Moderating role of alcohol tolerance in the association between excessive drinking and psychological distress: a cross-sectional study among agricultural workers in Japan

BMC Public Health
Background Excessive drinking is a known risk factor for psychological distress; however, the role of alcohol tolerance in this relationship remains unclear.
Syohei Miyamoto, Fumiya Tanji, Suguru Iwano, Atushi Iwasawa, Hidenobu Ohta, Kyoichi Ono   +5 more
doaj   +1 more source

The impact of borderline personality disorder and sub-threshold borderline personality disorder on the course of self-reported and clinician-rated depression in self-harming adolescents

Borderline Personality Disorder and Emotion Dysregulation, 2017
Background Studies on adults suggest that the presence of comorbid depression and Borderline Personality Disorder (BPD) is associated with an elevated risk of self-harming behaviours and that self-harming behaviours, when present, will have higher ...
Ruth-Kari Ramleth, Berit Groholt, Lien M. Diep, Fredrik A. Walby, Lars Mehlum   +4 more
doaj   +1 more source

The impact of COVID-19 stressors on psychological distress and suicidality in a nationwide community survey in Taiwan

Scientific Reports, 2022
COVID-19 stressors and psychological stress response are important correlates of suicide risks under the COVID-19 pandemic. This study aimed to investigate the prevalence of COVID-19 stress, its impact on mental health and associated risk factors among ...
Chia-Yi Wu, Ming-Been Lee, Pham Thi Thu Huong, Chia-Ta Chan, Chun-Yin Chen, Shih-Cheng Liao   +5 more
doaj   +1 more source