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Functional analysis of the UL24 protein of suid herpesvirus 1
Virus Genes, 2018The UL24 homologous genes are conserved in alphaherpesviruses. However, the proximity of the UL24 gene and the UL23 gene encoding for thymidine kinase (TK) in the genome of suid herpesvirus 1 (SuHV-1) makes it difficult to mutate UL24 without affecting the expression of the TK gene, and thus functional studies of the UL24 gene have lagged behind.
Guangzhi Tong +2 more
exaly +3 more sources
Archives of Virology, 2010
The aim of this study was to analyze the disordered regions (DRs) in the envelope and tegument proteins of three closely related herpesviruses: bovine herpesvirus 1, bovine herpesvirus 5 and suid herpesvirus 1. Tegument proteins showed a greater percentage of DRs than the envelope proteins did.
Heinemann Mb, Jenner Reis
exaly +3 more sources
The aim of this study was to analyze the disordered regions (DRs) in the envelope and tegument proteins of three closely related herpesviruses: bovine herpesvirus 1, bovine herpesvirus 5 and suid herpesvirus 1. Tegument proteins showed a greater percentage of DRs than the envelope proteins did.
Heinemann Mb, Jenner Reis
exaly +3 more sources
Molecular double-check strategy for the identification and characterization of Suid herpesvirus 1
Journal of Virological Methods, 2014Large scale vaccination with glycoprotein E (gE)-deleted marker vaccines and the rapid and reliable differentiation of wild-type and marker vaccine strains are important aspects in eradication programs for Suid herpesvirus 1 [SuHV-1, syn. Aujeszky's disease virus (ADV) or pseudorabies virus (PrV)].
Bernd Hoffmann +2 more
exaly +3 more sources
Veterinary Microbiology, 1999
The neural invasion of two virulent Suid Herpesvirus 1 (SHV1) strains was examined in neonatal pigs with or without maternal immunity. One-week-old pigs with comparable levels of maternal immunity (SN-titer = 12-48) were intranasally inoculated with 10(7.0) TCID50 of either of the Ka or E21 strains. The invasion of the strains was examined in the nasal
Hans Nauwynck, Maurice B Pensaert
exaly +3 more sources
The neural invasion of two virulent Suid Herpesvirus 1 (SHV1) strains was examined in neonatal pigs with or without maternal immunity. One-week-old pigs with comparable levels of maternal immunity (SN-titer = 12-48) were intranasally inoculated with 10(7.0) TCID50 of either of the Ka or E21 strains. The invasion of the strains was examined in the nasal
Hans Nauwynck, Maurice B Pensaert
exaly +3 more sources
Veterinary Microbiology, 1991
The genomic diversity among isolates of suid herpesvirus 1 (SHV-1) collected in the same herd and among clones from the same isolate was studied by restriction fragment pattern (RFP) analysis using BamHI. Tentatively defining a field strain as a transmissible entity, it was concluded that strains of SHV-1 commonly comprise distinguishable genomic ...
L S Christensen
exaly +3 more sources
The genomic diversity among isolates of suid herpesvirus 1 (SHV-1) collected in the same herd and among clones from the same isolate was studied by restriction fragment pattern (RFP) analysis using BamHI. Tentatively defining a field strain as a transmissible entity, it was concluded that strains of SHV-1 commonly comprise distinguishable genomic ...
L S Christensen
exaly +3 more sources
High frequency intergenomic recombination of suid herpesvirus 1 (SHV-1, Aujeszky's disease virus)
Archives of Virology, 1993Examples are given of observations made with field isolates of suid herpesvirus 1 (SHV-1) which indicate that intergenomic recombination is a common phenomenon associated with the virus. This was further confirmed by experimental co-infection of a pig with 2 virus strains with different, stable and easily identifiable genomic markers, followed by ...
L S Christensen, B Lomniczi
exaly +3 more sources
Veterinary Microbiology, 2012
Aujeszky's disease (AD), caused by Suid herpesvirus type 1 (SuHV-1), is an economically important disease in domestic swine. Thus, rigorous control programmes have been implemented and consecutively AD in domestic swine was successfully eradicated in many countries, including Austria.
Jolanta Kolodziejek +2 more
exaly +3 more sources
Aujeszky's disease (AD), caused by Suid herpesvirus type 1 (SuHV-1), is an economically important disease in domestic swine. Thus, rigorous control programmes have been implemented and consecutively AD in domestic swine was successfully eradicated in many countries, including Austria.
Jolanta Kolodziejek +2 more
exaly +3 more sources
Fish and Shellfish Immunology, 2014
Several studies have reported that molecules extracted from invertebrates have activity against different viruses, even against those that do not infect these organisms in their environment. One of the main mechanisms against pathogens in these organisms is the production of antimicrobial peptides.
M, Salas-Rojas +5 more
exaly +3 more sources
Several studies have reported that molecules extracted from invertebrates have activity against different viruses, even against those that do not infect these organisms in their environment. One of the main mechanisms against pathogens in these organisms is the production of antimicrobial peptides.
M, Salas-Rojas +5 more
exaly +3 more sources
Archives of Virology, 1992
Field isolates of suid herpesvirus 1 (Aujeszky's disease virus) from Poland and Hungary were identified by restriction fragment pattern analysis as derivatives of attenuated vaccine strains. The Polish isolates were found to be related to the BUK-TK-900 strain (Suivac A) which is widely used as a live vaccine in Poland, and the Hungarian isolates were ...
L S Christensen
exaly +3 more sources
Field isolates of suid herpesvirus 1 (Aujeszky's disease virus) from Poland and Hungary were identified by restriction fragment pattern analysis as derivatives of attenuated vaccine strains. The Polish isolates were found to be related to the BUK-TK-900 strain (Suivac A) which is widely used as a live vaccine in Poland, and the Hungarian isolates were ...
L S Christensen
exaly +3 more sources
Virus Research, 2009
Herpesviral DNA-binding protein (DBP) is a unique protein involved in viral DNA replication and genomic recombination. It binds and stabilizes the single-stranded DNA. It also forms the D-loops and promotes the strand invasion. To identify the functional regions and amino acid residues required for DNA binding and D-loop formation, we characterized ...
Chien-Yun Hsiang, Shih-Lu Wu
exaly +3 more sources
Herpesviral DNA-binding protein (DBP) is a unique protein involved in viral DNA replication and genomic recombination. It binds and stabilizes the single-stranded DNA. It also forms the D-loops and promotes the strand invasion. To identify the functional regions and amino acid residues required for DNA binding and D-loop formation, we characterized ...
Chien-Yun Hsiang, Shih-Lu Wu
exaly +3 more sources