Results 51 to 60 of about 670,868 (175)

Statistical properties of thermodynamically predicted RNA secondary structures in viral genomes

, 2008
By performing a comprehensive study on 1832 segments of 1212 complete genomes of viruses, we show that in viral genomes the hairpin structures of thermodynamically predicted RNA secondary structures are more abundant than expected under a simple random ...
A. Tuplin, C. Thurner, D.S.H. Chew, F. Lillo, F. Lillo, F. Lillo, F. Ratcliff, G.P. Schroth, H.O. Smith, J.S. Mattick, M. Spanò, M. Spanò, M.Y. Leung, P. Rice, P. Simmonds, P.E. Warburton, R. Cox, R. N. Mantegna, R.C. Lee, S. Miccichè, S.R. Eddy   +20 more
core   +1 more source

A systematic review of experimental evidence for antiviral effects of ivermectin and an in silico analysis of ivermectin's possible mode of action against SARS-CoV-2 [PDF]

, 2021
Viral infections remain a major cause of economic loss with an unmet need for novel therapeutic agents. Ivermectin is a putative antiviral compound; the proposed mechanism is the inhibition of nuclear translocation of viral proteins, facilitated by ...
Kinobe, Robert T., Owens, Leigh
core   +1 more source

Aujeszky’s Disease in a Grey Wolf (Canis lupus) in Poland

Viruses
Aujeszky’s disease (AD), caused by suid herpesvirus 1 (pseudorabies virus, PRV), is a highly contagious infection primarily affecting swine, with wild boars serving as an important reservoir in Europe.
Wojciech Wójcik, Anna Didkowska, Blanka Orłowska, Sabina Nowak, Bartosz Sell, Krzysztof Anusz, Florian Pfaff, Bernd Hoffmann   +7 more
doaj   +1 more source

Viruses in Horses with Neurologic and Respiratory Diseases. [PDF]

, 2019
Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Altan, Eda, Barnum, Samantha, Delwart, Eric, Deng, Xutao, Li, Yanpeng, Pusterla, Nicola, Sabino-Santos, Gilberto, Sawaswong, Vorthon   +7 more
core   +1 more source

Porcine Corneal Tissue and Xenozoonotic Risks: A Review of the Current Evidence

Xenotransplantation, Volume 32, Issue 6, November/December 2025.
ABSTRACT Corneal opacities affect millions worldwide, with corneal transplantation as the primary treatment. However, donor shortages remain a challenge, leaving thousands waiting for transplants. Xenotransplantation using porcine corneas has emerged as a promising alternative due to anatomical and physiological similarities with human corneas ...
Rodrigo Moreira, Heloisa Nascimento, Thaís Maria da Mata Martins, Gabriel Barbieri, Pedro Pires, Lucimeire N. Carvalho, Larissa R. Rosa, Augusto Almeida, Carmen Luz Pessuti, Henrique Ferrer, José Álvaro Pereira Gomes, Ernesto Goulart, Silvano Raia, Rubens Belfort Jr   +13 more
wiley   +1 more source

The effects of viral load on pseudorabies virus gene expression [PDF]

, 2010
Background Herpesvirus genes are classified into distinct kinetic groups on the basis of their expression dynamics during lytic growth of the virus in cultured cells at a high, typically 10 plaque-forming units/cell multiplicity of infection (
Judit S Tóth, Dóra Tombácz, Irma F Takács, Zsolt Boldogkői   +3 more
core   +2 more sources

Antiviral Activity of Carbon Dots: Strategies and Mechanisms of Action

Small Structures, Volume 6, Issue 3, March 2025.
Carbon dots are capable to interact with viruses through different mechanisms of action, having an antiviral and virucidal effect: inhibition of viral entry into the cells, disruption of viral replication, and damage of the virion structure. The COVID‐19 pandemic profoundly changes the perception of the impact of viral diseases on society and the ...
Plinio Innocenzi, Davide De Forni, Franco Lori   +2 more
wiley   +1 more source

The Pseudorabies Virus DNA Polymerase Accessory Subunit UL42 Directs Nuclear Transport of the Holoenzyme [PDF]

, 2016
Pseudorabies virus (PRV) DNA replication occurs in the nuclei of infected cells and requires the viral DNA polymerase. The PRV DNA polymerase comprises a catalytic subunit, UL30, and an accessory subunit, UL42, that confers processivity to the enzyme ...
Chang-Ming Liu, Hong-Li Wu, Li Feng, Li-Ping Huang, Wen-Juan Du, Yan-Wu Wei, Yi-Ping Wang   +6 more
core   +2 more sources

Marine Carotenoids: A Critical Review of Bioactivities, Bioavailability, and Therapeutic Potential

BioMed Research International, Volume 2025, Issue 1, 2025.
The marine environment is a significant origin of bioactive substances like carotenoids. Marine carotenoids are secondary metabolites with mechanism‐anchored benefits across redox, immune, and metabolic pathways, comprising antioxidant, anti‐inflammatory, antidiabetic, anticancer, and antimicrobial activities.
Gamal M. El-Sherbiny, Mohamed H. Kalaba, Baisakhi Banerjee   +2 more
wiley   +1 more source

Atividade antiviral de extratos de plantas medicinais disponíveis comercialmente frente aos herpesvírus suíno e bovino Antiviral activity of commercially available medicinal plants on suid and bovine herpesviruses

Revista Brasileira de Plantas Medicinais, 2012
O presente trabalho teve como objetivo pesquisar a atividade antiviral in vitro de plantas medicinais disponíveis comercialmente sobre herpesvírus suíno (SuHV-1) e bovino (BoHV-1).
V.M. Kaziyama, M.J.B. Fernandes, I.C. Simoni   +2 more
doaj   +1 more source