ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási +14 more
wiley +1 more source
Land Classification and Suitability for Development of Poor Regions in Terms of Resistive Economic Case study: Rigan County, South-East of Kerman Province [PDF]
Soil and water conservation, sustainable development and job creation were considered as one of the most important of the country's knowledge-based management strategies in poor and rural region. Soil survey, Watering ability, standard classification and
Kamran Moravej
doaj +1 more source
A Method to Evaluate the Suitability of Requirements Specifications for Offshore Projects [PDF]
Today, even the development of business information systems is subject to the global offshoring trend. With the division of development work in an inter-organizational and intercultural context, requirements specifications become the central means to communicate the development scope as explicitly as possible.
Overhage, Sven +2 more
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Suitability Evaluation of Urban Underground Space Development: A Case Study of Qingdao City
Urban underground space, as an underutilized land resource, holds tremendous potential and value. Efficient and rational development and utilization of this resource are key to addressing current urban challenges.
Ming Hao +7 more
doaj +1 more source
Evaluating the suitability of server network cards for software routers [PDF]
The advent of multicore CPUs has led to renewed interest in software routers built from commodity PC hardware[6, 5, 8, 7, 3, 4]. The typical approach to scaling network processing in these systems is to distribute packets, or rather flows of packets, across multiple cores that process them in parallel.
Maziar Manesh +7 more
openaire +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
On the Suitability of Programming Tasks for Automated Evaluation
For many programming tasks we would be glad to have some kind of automatic evaluation process. As an example, most of the programming contests use an automatic evaluation of the contestants' submissions. While this approach is clearly highly efficient, it also has some drawbacks.
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
An Evaluation of Suitable Functions for the Insulin Standard Curve [PDF]
The insulin radioimmunoassay technique used for human insulin has been modified for measuring rabbit insulin (i) at lower concentrations of insulin in plasma, and (ii) more precisely. Eleven algebraic functions were fitted in turn to fifty-three data sets. The goodness-of-fit was assessed in each case. It was concluded that a quadratic equation was the
openaire +3 more sources

