Results 51 to 60 of about 5,721,057 (309)

Evaluating the suitability of server network cards for software routers [PDF]

Proceedings of the Workshop on Programmable Routers for Extensible Services of Tomorrow, 2010
The advent of multicore CPUs has led to renewed interest in software routers built from commodity PC hardware[6, 5, 8, 7, 3, 4]. The typical approach to scaling network processing in these systems is to distribute packets, or rather flows of packets, across multiple cores that process them in parallel.
Maziar Manesh, Katerina J. Argyraki, Mihai Dobrescu, Norbert Egi, Kevin R. Fall, Gianluca Iannaccone, Eddie Kohler, Sylvia Ratnasamy   +7 more
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Annual corporate evaluation report 2010 [PDF]

, 2010
French version available in IDRC Digital Library: Rapport annuel sur l'évaluation 2010This report presents an in-depth analysis of selected evaluation topics, and notes the importance of the IDRC’s efforts in searching for improved approaches to ...
IDRC. Evaluation Unit
core  

An Evaluation of the Suitability of FPGAs for Embedded Vision Systems [PDF]

2005 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR'05) - Workshops, 2006
Reconfigurable hardware, in the form of Field Programmable Gate Arrays (FPGAs), is becoming increasingly attractive for digital signal processing problems, including image processing and computer vision tasks. The ability to exploit the parallelism often found in these problems, as well as the ability to support different modes of operation on a single
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Spatial suitability evaluation based on multisource data and random forest algorithm: a case study of Yulin, China

Frontiers in Environmental Science
With a large population and rapid urbanization, there are still many challenges to optimize the ecological-agricultural-urban space. Here, taking Yulin City, situated on the Loess Plateau of China as a case in point, we explored the spatial suitability ...
Anqi Li, Zhenkai Zhang, Zenglin Hong, Zenglin Hong, Zenglin Hong, Lingyi Liu, Lei Liu, Tariq Ashraf, Yuanmin Liu   +8 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Annual corporate evaluation report 2000 [PDF]

, 2000
French version available in IDRC Digital Library: Rapport annuel sur l'évaluation 2000The Annual Corporate Evaluation (ACE) Report is an element of the Centre's performance monitoring and reporting system.
IDRC. Evaluation Unit
core