Results 151 to 160 of about 23,478 (256)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Genomic Surveillance of BVDV in Southern Brazil: What Changed After a Decade in Rio Grande do Sul? [PDF]

Viruses
Baumbach LF, Alves RS, Camargo LJ, Sanguinet EO, Santos LS, Marian L, Birlem GE, Schroeder R, Barreto F, Costa JMN, Casagrande RA, Weber MN, Canal CW.   +12 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Therapeutic challenges and emerging strategies against carbapenem-resistant <i>Acinetobacter baumannii</i>. [PDF]

Curr Res Microb Sci
Yang C, Li J, Luo X, Song Z, Zhang J.
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Advancements in VO₂ measurement: bridging the gap between laboratory standards and field-based validity. [PDF]

Proc (Bayl Univ Med Cent)
de Souza Castro FA.
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Sistemas Participativos de Garantia (SPG) como alternativa de certificação de produtos orgânicos em sistemas agroalimentares sustentáveis

Colóquio
A certificação de produtos orgânicos por meio de Sistemas Participativos de Garantia (SPG) tem se apresentado como uma alternativa financeiramente mais acessível para a obtenção da certificação orgânica, mas também como um meio para a construção de ...
Ítalo de Paula Casemiro, Cláudio Becker   +1 more
doaj  

Hammersmith Infant Neurological Examination at 3 Months in Infants at Risk for Congenital Infections: A Cohort Study. [PDF]

J Paediatr Child Health
de Azambuja KCO, de Arguelho Oliveira Arguelho A, Weber MD, da Silva Dutra LM, de Souza TG, Soares-Marangoni D.   +5 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source