Results 101 to 110 of about 21,848 (263)

Responsiveness of emergency obstetric care systems in low- and middle-income countries: a critical review of the "third delay". [PDF]

, 2012
We reviewed the evidence on the duration, causes and effects of delays in providing emergency obstetric care to women attending health facilities (the third delay) in low- and middle-income countries. We performed a critical literature review using terms
Cavallaro, Francesca L, Marchant, Tanya J   +1 more
core   +1 more source

cTfh Cell Activation and Changes in BTLA and LAG‐3 Expression Differentially Associate With Poor Pregnancy Outcome in Plasmodium falciparum Placental Malaria

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Continuous exposure to antigens drives the activation of circulating T follicular helper (cTfh) cells, promoting high‐affinity antibody production. However, sustained stimulation may impair their function through the upregulation of immunoregulatory markers like B and T lymphocyte attenuator (BTLA) and Lymphocyte-activation gene 3 (LAG-3).
Bernard Marie Zambo Bitye, Chris Marco Mbianda Nana, Bodin Darcisse Kwanou Tchakounte, Balotin Fogang, Berenice Kenfack Tekougang Zangue, Reine Seumko’o Medouen Ndeumou, Lawrence Ayong, Rosette Megnekou, Poorani Gurumallesh Prabu   +8 more
wiley   +1 more source

A Randomized Open-Label Evaluation of the Antimalarial Prophylactic Efficacy of Azithromycin-Piperaquine versus Sulfadoxine-Pyrimethamine in Pregnant Papua New Guinean Women

Antimicrobial Agents and Chemotherapy, 2019
Emerging malaria parasite sulfadoxine-pyrimethamine (SP) resistance has prompted assessment of alternatives for intermittent preventive treatment in pregnancy (IPTp).
B. Moore, J. Benjamin, Roselyn Tobe, M. Ome-Kaius, Gumul Yadi, Bernadine Kasian, Charles Kong, L. Robinson, M. Laman, I. Mueller, S. Rogerson, T. Davis   +11 more
semanticscholar   +1 more source

Polyparasitism and Anaemia Among Women of Reproductive Age in Kilifi County—Kenya

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Background Polyparasitism is commonly associated with Plasmodium species, Schistosoma species and soil‐transmitted helminths. Anaemia results from a variety of causes, including parasitic infections. Women of reproductive age (WRA) and children below the age of five are disproportionately affected by polyparasitic infections, putting them at risk of ...
Matano Mjomba, Simon Muriu, Victor Tunje Jeza, Pedro P. Chieffi   +3 more
wiley   +1 more source

Antimalarial drug sulfadoxine induces gametocytogenesis in Plasmodium berghei

Malaria Journal
Background The spread of antimalarial drug resistance parasites is a major obstacle in eliminating malaria in endemic areas. This increases the urgency for developing novel antimalarial drugs with improved profiles to eliminate both sensitive and ...
Wihda Aisarul Azmi, Andita Fitri Mutiara Rizki, Achmad Shidiq, Yenny Djuardi, I Made Artika, Josephine Elizabeth Siregar   +5 more
doaj   +1 more source

Organometallic Conjugates of the Drug Sulfadoxine for Combatting Antimicrobial Resistance.

Chemistry, 2018
Fourteen novel arene RuII , and cyclopentadienyl (Cpx ) RhIII and IrIII complexes containing an N,N'-chelated pyridylimino- or quinolylimino ligand functionalized with the antimalarial drug sulfadoxine have been synthesized and characterized, including ...
P. Chellan, V. Avery, Sandra Duffy, J. Triccas, Gayathri Nagalingam, Christina C Tam, Luisa W Cheng, Jenny Liu, K. Land, G. Clarkson, I. Romero‐Canelón, P. Sadler   +11 more
semanticscholar   +1 more source

Molecular evidence of incipient speciation within Anopheles gambiae s.s. in West Africa [PDF]

, 2001
We karyotyped and identified by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) analysis Anopheles gambiae s.s. samples collected in several African countries. The data show the existence of two non-panmictic molecular forms,
Akogbeto, M, Coluzzi, M, della Torre, A, Dossou-Yovo, J, Fanello, C, Favia, G, Petrarca, V   +6 more
core   +1 more source

Unveiling the Antimalarial Potential of Leaf Extracts of Mussaenda erythrophylla Schum. & Thonn. and Mussaenda philippica Dona Luz x M. flava in Mice

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Malaria remains a major global public health concern, particularly in tropical regions. The increasing resistance to the current antimalarial drugs highlights the urgent need for new and effective therapies. Medicinal plants offer a promising source of novel and affordable antimalarial compounds for drug development.
Prapaporn Chaniad, Arisara Phuwajaroanpong, Walaiporn Plirat, Atthaphon Konyanee, Parnpen Viriyavejakul, Abdi Wira Septama, Chuchard Punsawad, Rajib Chowdhury   +7 more
wiley   +1 more source

Evidence of triple mutant Pfdhps ISGNGA haplotype in Plasmodium falciparum isolates from North-east India: An analysis of sulfadoxine resistant haplotype selection

Genomics Data, 2016
Background: North-east region of India has consistent role in the spread of multi drug resistant Plasmodium (P.) falciparum to other parts of Southeast Asia.
Manuj K. Das, Sumi Chetry, Mohan C. Kalita, Prafulla Dutta   +3 more
doaj   +1 more source

Prevalence of Plasmodium falciparum parasites resistant to sulfadoxine/pyrimethamine in the Democratic Republic of the Congo: emergence of highly resistant pfdhfr/pfdhps alleles

Journal of Antimicrobial Chemotherapy, 2018
Background In 2005, the Democratic Republic of the Congo (DRC) switched to artesunate/amodiaquine as the first-line antimalarial in response to increasing sulfadoxine/pyrimethamine resistance and adopted intermittent preventive treatment using ...
P. Nkoli Mandoko, Florent Rouvier, Lebon Matendo Kakina, D. Moke Mbongi, Christine Latour, J. Losimba Likwela, D. Ngoyi Mumba, S. K. Bi Shamamba, Jean-Jacques Tamfum Muyembe, L. Muepu Tshilolo, D. Parzy, V. Sinou   +11 more
semanticscholar   +1 more source