Results 81 to 90 of about 21,848 (263)

Efficacy of chloroquine, sulphadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria in Kajo Keji county, Sudan. [PDF]

, 2004
To provide advice on the rational use of antimalarial drugs, Médecins Sans Frontières conducted a randomized, an open label efficacy study in Kajo Keji, an area of high transmission of malaria in southern Sudan.
Epicentre, Krishna S, Kshirsagar NA, National Malaria Administration/Unicef, Ochong EO, Omari AA, Seidlein L, UN/OCHA, Vugt M, WHO, WHO, WHO, WHO, WHO/Roll Back Malaria   +13 more
core   +2 more sources

Artemisinin‐Based Combination Therapies in East Africa: A Systematic Review of Quality, Clinical Efficacy, and Regulatory Progress Towards Sustainable Malaria Control

Tropical Medicine &International Health, Volume 31, Issue 3, Page 254-273, March 2026.
ABSTRACT Background Malaria is a major public health issue in East Africa, leading to widespread illness and fatalities, especially among vulnerable populations such as children under 5 years of age and pregnant women. Artemisinin‐based combination therapies (ACTs) are the primary treatment modality; however, their efficacy is undermined by the ...
Yesuneh Tefera Mekasha, Addisu Afrassa Tegegne, Tapfumanei Mashe, Million Girma, Gemmechu Hasen, Sileshi Belew   +5 more
wiley   +1 more source

Sulfadoxine-pyrimethamine plus chloroquine or amodiaquine for uncomplicated falciparum malaria: a randomized, multisite trial to guide national policy in Uganda. [PDF]

, 2005
The use of combinations of inexpensive drugs for the treatment of malaria in Africa has been proposed as an interim policy while awaiting the widespread availability of more effective regimens.
Bakyaita, Nathan, Banek, Kristin, Dorsey, Grant, Kamya, Moses R, Kilian, Albert, Kironde, Fred, Nsobya, Sam, Reingold, Arthur, Rosenthal, Philip J, Staedke, Sarah G, Talisuna, Ambrose, Wabwire-Mangen, Fred, Yeka, Adoke   +12 more
core   +1 more source

Strengthening Newborn Screening: A Pilot Health Program Management for Sickle Cell Disease in Côte d’Ivoire

Anemia, Volume 2026, Issue 1, 2026.
Background The World Health Assembly (WHA) resolution urges African countries with a high burden of sickle cell anemia (SCA) to design and implement national programs emphasizing early identification through newborn screening (NBS) and prompt access to adequate preventive care.
Kouassi Gustave Koffi, Romuald Sery Dasse, Sara Akou Bognini, Clotaire Danho Nanho, Ines Kouakou, Mireille Yayo, Evelyne Lasme, Kadona Melissa, Yannick Kouassi, Cynthia N’dri, Dohoma Alexis Silue, Ismael Kamara, Soro Noundjo, Dieket Ruth, Emeraude N’dhatz, Boidy Kouakou, Sawadogo Duni, Sanogo Ibrahim, Bassimbie-Jeanette Danho, Duran Canatan   +19 more
wiley   +1 more source

Sulfadoxine-Pyrimethamine Exhibits Dose-Response Protection Against Adverse Birth Outcomes Related to Malaria and Sexually Transmitted and Reproductive Tract Infections

Clinical Infectious Diseases, 2017
Summary Compared to 0–1 dose of intermittent preventive treatment of malaria using sulfadoxine-pyrimethamine, ≥2 doses protects pregnant women against adverse birth outcomes attributable to malaria infection and to curable sexually transmitted and ...
R. Chico, E. B. Chaponda, E. B. Chaponda, C. Ariti, D. Chandramohan   +4 more
semanticscholar   +1 more source

Examining catastrophic costs and benefit incidence of subsidized antiretroviral treatment (ART) programme in south-east Nigeria.

, 2008
OBJECTIVES: To examine the extent to which costs of subsidized antiretrovirals treatment (ART) programmes are catastrophic and the benefit incidence that accrues to different population groups.
Chukwuka, Chinwe, Dike, Nkem, Ichoku, Hyacinth, Onoka, Chima, Onwujekwe, Obinna, Onyedum, Cajetan, Uzochukwu, Benjamin   +6 more
core   +1 more source

Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial. [PDF]

, 2018
BACKGROUND: Primaquine and methylene blue are gametocytocidal compounds that could prevent Plasmodium falciparum transmission to mosquitoes. We aimed to assess the efficacy and safety of primaquine and methylene blue in preventing human to mosquito ...
Bousema, Teun, Bradley, John, Brown, Joelle M, Chen, Ingrid, Diarra, Kalifa, Diawara, Halimatou, Dicko, Alassane, Drakeley, Chris, Gosling, Roly, Hwang, Jimee, Issiaka, Djibrilla, Keita, Sekouba, Kone, Daouda T, Lanke, Kjerstin, Mahamar, Almahamoudou, McCulloch, Charles, Müller, Olaf, Roh, Michelle E, Sanogo, Koualy, Soumare, Harouna M, Srinivasan, Vinay, Stone, Will JR, Traore, Sekou F   +22 more
core   +2 more sources

Prevalence of Plasmodium Species Using Rapid Diagnostic Tests in Cameroon: First‐Year Data From Routine Malaria Surveillance

BioMed Research International, Volume 2026, Issue 1, 2026.
Background Malaria remains a major public health concern in Cameroon. Although Plasmodium falciparum is the predominant parasite, the prevalence of other Plasmodium species remains poorly documented due to the absence of a formal surveillance system.
Raymond Ngomdjum Tabue, Flora Neh, Elvira Evina, Dominique Amougou Bomba, Junior Voundi Voundi, Jean Fosso, Albert Meka Zeh, Yoel A. Klug   +7 more
wiley   +1 more source

Sulfadoxine/Pyrimethamine Intermittent Preventive Treatment for Malaria during Pregnancy

Emerging Infectious Diseases, 2010
For monitoring efficacy of sulfadoxine/pyrimethamine intermittent preventive treatment for malaria during pregnancy, data obtained from studies of children seemed inadequate. High prevalence of triple and quadruple mutants in the dihydropteroate synthase
Philippe Deloron, Gwladys Bertin, Valérie Briand, Achille Massougbodji, Michel Cot   +4 more
doaj   +1 more source

Molecular markers of resistance to amodiaquine plus sulfadoxine–pyrimethamine in an area with seasonal malaria chemoprevention in south central Niger

Malaria Journal, 2018
In Niger, malaria transmission is markedly seasonal with most of the disease burden occurring in children during the rainy season. Seasonal malaria chemoprevention (SMC) with amodiaquine plus sulfadoxine–pyrimethamine (AQ + SP) is recommended in the ...
R. Grais, I. Laminou, Lynda Woi-Messe, Rockyath Makarimi, Seidou H. Bouriema, C. Langendorf, A. Amambua-Ngwa, U. d’Alessandro, P. Guérin, T. Fandeur, C. Sibley   +10 more
semanticscholar   +1 more source