Results 111 to 120 of about 20,006 (291)

Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance [PDF]

, 2013
The biggest threat to the war on malaria is the continued evolution of drug resistance by the parasite. Resistance to almost all currently available antimalarials now exists in Plasmodium falciparum which causes the most suffering among all human malaria
Mwangi, J.M., Ranford-Cartwright, L.C.
core   +1 more source

Therapeutic efficacy of sulfadoxine-pyrimethamine for Plasmodium falciparum malaria.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2005
To assess the therapeutic efficacy of sulfadoxinepyrimethamine (SP) after 5 years of use as first-line treatment of uncomplicated Plasmodium falciparum malaria, and thus guide the selection of artemisinin-based combination therapy in Mpumalanga, South Africa.An open-label, in vivo therapeutic efficacy study of patients with uncomplicated P.
Mabuza, Aaron, Govere, John, La Grange, Kobus, Mngomezulu, Nicros, Allen, Elizabeth, Zitha, Alpheus, Mbokazi, Frans, Durrheim, David, Barnes, Karen   +8 more
openaire   +4 more sources

Occurrence, ecological, and health risk assessment of antibiotics in water from the Karst River during influenza season

River, Volume 3, Issue 4, Page 389-398, November 2024.
Abstract The widespread use of antibiotics has significantly increased their presence in aquatic environments, particularly in sensitive Karst River systems. In this study, the distribution and ecological, human health, and resistance selection risk assessment of 44 antibiotics in the typical Karst River, Lijiang River, were investigated during the ...
Xiong Pan, Wenjie Fu, Yuyi Yang
wiley   +1 more source

Evidence of triple mutant Pfdhps ISGNGA haplotype in Plasmodium falciparum isolates from North-east India: An analysis of sulfadoxine resistant haplotype selection

Genomics Data, 2016
Background: North-east region of India has consistent role in the spread of multi drug resistant Plasmodium (P.) falciparum to other parts of Southeast Asia.
Manuj K. Das, Sumi Chetry, Mohan C. Kalita, Prafulla Dutta   +3 more
doaj   +1 more source

Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia [PDF]

, 2017
Hydroxyurea treatment is recommended for children with sickle cell anemia (SCA) living in high-resource malaria-free regions, but its safety and efficacy in malaria-endemic sub-Saharan Africa, where the greatest sickle-cell burden exists, remain unknown.
Hodges, James S., Hume, Heather A., John, Chandy C., Kasirye, Phillip, Lane, Adam, Latham, Teresa S., Ndugwa, Christopher M., Opoka, Robert O., Ware, Russell E.   +8 more
core   +2 more sources

Clinical and laboratory predictors for bacteremia in critically ill calves

Journal of Veterinary Internal Medicine, Volume 38, Issue 6, Page 3367-3383, November/December 2024.
Abstract Background Sepsis is a main contributor to calf mortality, but diagnosis is difficult. Objectives Develop and validate a predictive model for bacteremia in critically ill calves (CIC). Animals A total of 334 CIC, sampled for blood culture. Methods Cross‐sectional study.
Mathilde L. Pas, Jade Bokma, Filip Boyen, Bart Pardon   +3 more
wiley   +1 more source

Efficacy and Safety of Azithromycin-Chloroquine versus Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment of Plasmodium falciparum Malaria Infection in Pregnant Women in Africa: An Open-Label, Randomized Trial

PLoS ONE, 2016
Background The World Health Organization recommends intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) in African regions with moderate to high malaria transmission.
J. Kimani, K. Phiri, S. Kamiza, S. Duparc, A. Ayoub, R. Rojo, J. Robbins, Russell Orrico, Pol Vandenbroucke   +8 more
semanticscholar   +1 more source

Assessment of a national voucher scheme to deliver insecticide-treated mosquito nets to pregnant women.

, 2010
BACKGROUND: The benefits of a health-related intervention may be compromised by the challenges of delivering the intervention on a large scale. We analyzed the process involved in the Tanzania National Voucher Scheme, a system for delivering insecticide ...
Armstrong-Schellenberg, Joanna, Bruce, Jane, Hanson, Kara, Jones, Caroline, Marchant, Tanya, Mponda, Hadji, Nathan, Rose, Schellenberg, David, Sedekia, Yovitha   +8 more
core   +2 more sources

S3 guideline: Diagnosis and treatment of epidermal necrolysis (Stevens‐Johnson syndrome and toxic epidermal necrolysis) – Part 1: Diagnosis, initial management, and immunomodulating systemic therapy

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 22, Issue 10, Page 1448-1466, October 2024.
Summary Stevens‐Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are rare, predominantly drug‐induced, acute, life‐threatening diseases of skin and mucosae. SJS and TEN are nowadays considered variants of one disease entity with varying degrees of severity called epidermal necrolysis (EN). EN is associated with high morbidity and mortality and
Ruben Heuer, Maren Paulmann, Thorsten Annecke, Björn Behr, Katharina Boch, Anja M. Boos, Knut Brockow, Lars E. French, Jochen Gille, Verena Gundlach, Bernd Hartmann, Peter Höger, Silke C. Hofmann, Tobias Klein, Marcus Lehnhardt, Yvonne Liß, Philip Maier, Philipp Mandel, Nicos Marathovouniotis, Finnja Marlok, Hans Mittelviefhaus, Uwe Pleyer, Marie Pradeau, Katharina Rall, Siegbert Rieg, Heike Rittner, Frank Sander, Stefan Schnitzler, Christina Schut, Annette Stolle, Artem Vorobyev, Bettina Wedi, Johannes Weiss, Maximilian Zepp, Mirjana Ziemer, Maja Mockenhaupt, Alexander Nast   +36 more
wiley   +1 more source

Comparative Evaluation of the Dynamics of Parameters of Cell-Mediated Immunity under the Influence of Different Therapies for Chronic Acquired Toxoplasmosis

Aktualʹnaâ Infektologiâ, 2015
The article presents a comparative evaluation of the dynamics of parameters of cell-mediated immunity in patients under the influence of different therapies for chronic acquired toxoplasmosis (CAT).
O.V. Bobrova, Anuar al Hatib
doaj   +1 more source