Results 131 to 140 of about 20,006 (291)

Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi

Malaria Journal, 2016
BackgroundMalawi experienced prolonged use of sulfadoxine/pyrimethamine (SP) as the front-line anti-malarial drug, with early replacement of chloroquine and delayed introduction of artemisinin-based combination therapy.
M. Ravenhall, E. D. Benavente, M. Mipando, Anja T. R. Jensen, C. Sutherland, C. Roper, N. Sepúlveda, D. Kwiatkowski, J. Montgomery, K. Phiri, Anja D Terlouw, A. Craig, S. Campino, Harold Ocholla, T. Clark   +14 more
semanticscholar   +1 more source

Efficacy of chloroquine, sulphadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria in Kajo Keji county, Sudan. [PDF]

, 2004
To provide advice on the rational use of antimalarial drugs, Médecins Sans Frontières conducted a randomized, an open label efficacy study in Kajo Keji, an area of high transmission of malaria in southern Sudan.
Epicentre, Krishna S, Kshirsagar NA, National Malaria Administration/Unicef, Ochong EO, Omari AA, Seidlein L, UN/OCHA, Vugt M, WHO, WHO, WHO, WHO, WHO/Roll Back Malaria   +13 more
core   +2 more sources

The remarkable tenacity of sulfadoxine-pyrimethamine [PDF]

The Lancet Infectious Diseases, 2019
Titus H. Divala, Lauren M. Cohee, Miriam K. Laufer   +2 more
openaire   +4 more sources

Antimalarial Drug Resistance: A Brief History of Its Spread in Indonesia

Drug Design, Development and Therapy, 2023
Loeki Enggar Fitri,1,2 Aulia Rahmi Pawestri,1,2 Nuning Winaris,1,2 Agustina Tri Endharti,1 Alif Raudhah Husnul Khotimah,3,4 Hafshah Yasmina Abidah,3,4 John Thomas Rayhan Huwae3,5 1Department of Parasitology Faculty of Medicine, Universitas Brawijaya ...
Fitri LE, Pawestri AR, Winaris N, Endharti AT, Khotimah ARH, Abidah HY, Huwae JTR   +6 more
doaj  

Evaluation of Three Rapid Tests for Diagnosis of P. Falciparum and P. Vivax Malaria in Colombia. [PDF]

, 2006
The diagnostic capacity of three malaria rapid diagnostic tests (RDTs), NOW-Malaria-ICT, OptiMAL-IT, and Paracheck-Pf, was evaluated against expert microscopy in Colombia. We tested 896 patients, of whom microscopy confirmed 139 P.
Angarita, B, Counihan, H, Gordillo, F, Guthmann, J P, Hamade, P, Hill, O, van den Broek, I   +6 more
core   +1 more source

Atovaquone and proguanil hydrochloride compared with chloroquine or pyrimethamine/sulfadoxine for treatment of acute Plasmodium falciparum malaria in Peru

Brazilian Journal of Infectious Diseases
The efficacy and safety of a fixed-dose combination of atovaquone and proguanil hydrochloride (MalaroneTM) were compared with chloroquine or pyrimethamine/sulfadoxine in patients with acute falciparum malaria in northern Peru.
A. Llanos-Cuentas, P. Campos, M. Clendenes, C. J. Canfield, D. B. A. Hutchinson   +4 more
doaj   +1 more source

Audit of failure rate of sulfadoxine/pyrimetham combined with chloroquine to treat falciparum malaria at single fourteen-day follow-up

South African Family Practice, 2002
Objective: To assess the failure rate of the present first line treatment regime for uncomplicated falciparum malaria of sulfadoxine/pyrimethamine combined with chloroquine. Design: A before-after study. Setting: Ndumo Clinic, Ingwavuma District, South
C.H. Vaughan Williams, C. La Cock, G.F.J. Henry, A.J. Ross   +3 more
doaj   +1 more source

Polymorphism in dhfr/dhps genes, parasite density and ex vivo response to pyrimethamine in Plasmodium falciparum malaria parasites in Thies, Senegal☆ [PDF]

, 2014
Resistance to sulfadoxine–pyrimethamine (SP) in Plasmodium falciparum malaria parasites is associated with mutations in the dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes, and these mutations have spread resistance worldwide. SP,
Bei, Amy K., Daniels, Rachel, Dieye, Baba, Lukens, Amanda, Mbaye, Aminata, Mboup, Souleymane, Ndiaye, Daouda, Ndiaye, Yaye D., Ndir, Omar, Tyne, Daria Van, Valim, Clarissa, Volkman, Sarah, Wirth, Dyann F.   +12 more
core   +1 more source

Therapeutic efficacy of sulfadoxine-pyrimethamine, amodiaquine and the sulfadoxine-pyrimethamine-amodiaquine combination against uncomplicated Plasmodium falciparum malaria in young children in Cameroon

Bulletin of the World Health Organization, 2002
OBJECTIVE: To evaluate the therapeutic efficacy of sulfadoxine-pyrimethamine, amodiaquine, and the sulfadoxine-pyrimethamine-amodiaquine combination for the treatment of uncomplicated Plasmodium falciparum malaria in young children in Cameroon.
Basco Leonardo K., Same-Ekobo Albert, Ngane Vincent Foumane, Ndounga Mathieu, Metoh Theresia, Ringwald Pascal, Soula Georges   +6 more
doaj  

Differential infectivity of gametocytes after artemisinin-based combination therapy of uncomplicated falciparum malaria

African Journal of Laboratory Medicine, 2018
Background: Most malaria-endemic countries use artemisinin-based combination therapy (ACT) as their first-line treatment. ACTs are known to be highly effective on asexual stages of the malaria parasite.
Dinkorma T. Ouologuem, Cheick O. Kone, Bakary Fofana, Bakary Sidibe, Amadou H. Togo, Demba Dembele, Sekou Toure, Sekou Koumare, Ousmane Toure, Issaka Sagara, Abdoulaye Toure, Adama Dao, Ogobara K. Doumbo, Abdoulaye A. Djimde   +13 more
doaj   +1 more source