Bulletin of the World Health Organization, 2002 OBJECTIVE: To evaluate the therapeutic efficacy of sulfadoxine-pyrimethamine, amodiaquine, and the sulfadoxine-pyrimethamine-amodiaquine combination for the treatment of uncomplicated Plasmodium falciparum malaria in young children in Cameroon.
Basco Leonardo K. +6 more
doaj
Sequential treatment with quinine and mefloquine or quinine and pyrimethamine-sulfadoxine for falciparum malaria. [PDF]
, 1977 Anthony Hall +8 more
openalex +1 more source
CPT: Pharmacometrics & Systems Pharmacology, 2017 Sulfadoxine/pyrimethamine is recommended for intermittent preventative treatment of malaria during pregnancy. Data from 98 women during pregnancy and 77 after delivery in four African countries were analyzed using nonlinear mixed‐effects modeling to ...
M. D. Kock +6 more
semanticscholar +1 more source
Bulletin of the World Health Organization, 2002 OBJECTIVE: To assess the efficacy of chloroquine and sulfadoxine/pyrimethamine in the treatment of uncomplicated Plasmodium falciparum infections in Somalia.
Warsame M. +6 more
doaj
Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization [PDF]
, 1997 Ping Wang +3 more
openalex +1 more source
Intermittent Preventive Treatment with Sulfadoxine–Pyrimethamine: More than Just an Antimalarial?
American Journal of Tropical Medicine and Hygiene, 2017 Malaria in pregnancy is associated with increased risk for both maternal and neonatal adverse outcomes, notably low birthweight and neonatal mortality.
J. Gutman, L. Slutsker
semanticscholar +1 more source
Short Report: Association Between Chloroquine and Amodiaquine Resistance and Allelic Variation in the Plasmodium Falciparum Multiple Drug Resistance 1 Gene and the Chloroquine Resistance Transporter Gene in Isolates from the Upper Nile in Southern Sudan. [PDF]
, 2003 Amodiaquine, a 4-aminoquinoline compound, is being considered as an alternative to chloroquine and pyrimethamine/sulfadoxine where resistance in Plasmodium falciparum to both drugs has been selected.
Keus, K +3 more
core +1 more source
Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria [PDF]
, 1998 Tony Triglia +4 more
openalex +1 more source
Low-Dose Treatment with Sulfadoxine-Pyrimethamine Combinations Selects for Drug-Resistant Plasmodium falciparum Strains [PDF]
, 1999 Jürgen F. J. Kun +4 more
openalex +1 more source
Malaria Journal, 2016 Substandard and falsified anti-malarial medicines pose a serious threat to public health, especially in low-income countries. Appropriate technologies for drug quality analysis in resource-limited settings are important for the surveillance of the formal
Felix Khuluza +3 more
semanticscholar +1 more source