Results 141 to 150 of about 21,848 (263)

The management and treatment of malaria [PDF]

, 1989
Falciparum malaria can create severe complications. Antimalarial drugs such as quinine or chloroquine help in the treatment and management to these complications. The use of chemoprophylaxis is a must for persons travelling abroad to countries subject to
Gilles, Herbert M.
core  

Differential infectivity of gametocytes after artemisinin-based combination therapy of uncomplicated falciparum malaria

African Journal of Laboratory Medicine, 2018
Background: Most malaria-endemic countries use artemisinin-based combination therapy (ACT) as their first-line treatment. ACTs are known to be highly effective on asexual stages of the malaria parasite.
Dinkorma T. Ouologuem, Cheick O. Kone, Bakary Fofana, Bakary Sidibe, Amadou H. Togo, Demba Dembele, Sekou Toure, Sekou Koumare, Ousmane Toure, Issaka Sagara, Abdoulaye Toure, Adama Dao, Ogobara K. Doumbo, Abdoulaye A. Djimde   +13 more
doaj   +1 more source

Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants.

, 2009
Intermittent preventive treatment in infants (IPTi) is an effective and safe malaria control strategy. However, it remains unclear what antimalarials should be used to replace sulfadoxine-pyrimethamine (SP) when and where SP is no longer an effective ...
Cairns, Matthew, Gosling, Roly, Gesase, Samwel, Mosha, Jacklin, Greenwood, Brian, Chandramohan, Daniel   +5 more
core   +1 more source

Use of thin-layer chromatography to detect counterfeit sulfadoxine/pyrimethamine tablets with the wrong active ingredient in Malawi

Malaria Journal, 2016
Substandard and falsified anti-malarial medicines pose a serious threat to public health, especially in low-income countries. Appropriate technologies for drug quality analysis in resource-limited settings are important for the surveillance of the formal
Felix Khuluza, Stephen Kigera, R. Jähnke, L. Heide   +3 more
semanticscholar   +1 more source

Molecular monitoring of Plasmodium falciparum super-resistance to sulfadoxine–pyrimethamine in Tanzania

Malaria Journal, 2016
Sulfadoxine–pyrimethamine (SP) is recommended for prophylactic treatment of malaria in pregnancy while artemisinin combination therapy is the recommended first-line anti-malarial treatment.
R. Kavishe, R. Kaaya, Sidsel Nag, Camilla Krogsgaard, Jakob Ginsbak Notland, Adellaida A. Kavishe, D. Ishengoma, C. Roper, M. Alifrangis   +8 more
semanticscholar   +1 more source

Clinical and parasitological efficacy of artesunate and sulfadoxine-pyrimethamine (AS+SP) for the treatment of uncomplicated falciparum malaria in different transmission settings in India

Journal of Vector Borne Diseases
Background & objectives: In 2010, artesunate and sulfadoxine-pyrimethamine (AS+SP) were adopted as the first-line artemisinin based combination therapy for treatment of uncomplicated Plasmodium falciparum malaria in India. Continuous therapeutic efficacy
Ritesh Ranjha, Rajendra Baharia, H Chalageri Vani, Bina Srivastava, Naseem Ahmed, Supriya Sharma, Prashant Kumar Mallick, Anupkumar R Anvikar, Praveen Kumar Bharti   +8 more
doaj   +1 more source

Development and validation of RP-HPLC method for simultaneous estimation of sulfadoxine and pyrimethamine in tablet dosage form using diclofenac as internal standard

, 2018
Sulfadoxine and pyrimethamine are often formulated together and used in the treatment of malaria especially in pregnant women serving as a prophylaxis.
Akwasi Acheampong, A. Gyebi, Godfred Darko, J. Apau, Wilfred Owusu Gyasi, Sylvester Addai-Arhin   +5 more
semanticscholar   +1 more source

Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries.

PLoS ONE, 2014
The dihydropteroate synthase (dhps) genes of 44 P. malariae strains from four Asian countries were isolated. Only a limited number of polymorphisms were observed.
Naowarat Tanomsing, Mayfong Mayxay, Paul N Newton, Francois Nosten, Christiane Dolecek, Tran Tinh Hien, Nicholas J White, Nicholas P J Day, Arjen M Dondorp, Mallika Imwong   +9 more
doaj   +1 more source

Atovaquone and proguanil hydrochloride compared with chloroquine or pyrimethamine/sulfadoxine for treatment of acute Plasmodium falciparum malaria in Peru

Brazilian Journal of Infectious Diseases, 2001
The efficacy and safety of a fixed-dose combination of atovaquone and proguanil hydrochloride (MalaroneTM) were compared with chloroquine or pyrimethamine/sulfadoxine in patients with acute falciparum malaria in northern Peru.
Llanos-Cuentas A., Campos P., Clendenes M., Canfield C. J., Hutchinson D. B. A.   +4 more
doaj  

Fitness of sulfadoxine-resistant Plasmodium berghei harboring a single mutation in dihydropteroate synthase (dhps).

Acta Tropica, 2021
M. Yamauchi, M. Hirai, Shin-Ichiro Tachibana, Toshiyuki Mori, Toshihiro Mita   +4 more
semanticscholar   +1 more source