The Pleiotropic Regulator AdpA Regulates the Removal of Excessive Sulfane Sulfur in Streptomyces coelicolor [PDF]
Antioxidants, 2023 Reactive sulfane sulfur (RSS), including persulfide, polysulfide, and elemental sulfur (S8), has important physiological functions, such as resisting antibiotics in Pseudomonas aeruginosa and Escherichia coli and regulating secondary metabolites ...
Ting Lu +5 more
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The conversion of H2S to sulfane sulfur [PDF]
Nature Reviews Molecular Cell Biology, 2012 In a recently published Review article (H2S signalling through protein sulfhydration and beyond. Nature Rev. Mol. Cell Biol. 13, 499–507 (2012))1, Paul and Snyder use the term 'sulfhydration' to define a protein modification involving hydrogen sulfide (H2S) in which “the sulfhydryl group of a reactive Cys is modified to an -SSH group”.
John I Toohey
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Modified cyclodextrins solubilize elemental sulfur in water and enable biological sulfane sulfur delivery. [PDF]
Chem Sci, 2020 An important form of biological sulfur is sulfane sulfur, or S 0 , which is found in polysulfide and persulfide compounds as well as in elemental sulfur. Sulfane sulfur, often in the form of S 8 , functions as a key energy source in the metabolic processes of ...
Bolton SG, Pluth MD.
europepmc +4 more sources
Targeting hepatic sulfane sulfur/hydrogen sulfide signaling pathway with α-lipoic acid to prevent diabetes-induced liver injury via upregulating hepatic CSE/3-MST expression [PDF]
Diabetology & Metabolic Syndrome, 2022 Background Diabetes-induced liver injury is a complication of diabetes mellitus of which there are no approved drugs for effective treatment or prevention.
George J. Dugbartey +6 more
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Using resonance synchronous spectroscopy to characterize the reactivity and electrophilicity of biologically relevant sulfane sulfur [PDF]
Redox Biology, 2019 Sulfane sulfur is common inside cells, playing both regulatory and antioxidant roles. However, there are unresolved issues about its chemistry and biochemistry.
Huanjie Li +10 more
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Escherichia coli Uses Separate Enzymes to Produce H2S and Reactive Sulfane Sulfur From L-cysteine [PDF]
Frontiers in Microbiology, 2019 Hydrogen sulfide (H2S) has been proposed to have various physiological functions, and it may function through reactive sulfane sulfur. Since the two sulfur forms often coexist, they are normally considered interchangeable.
Kai Li +7 more
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The glial Gomori-positive material is sulfane sulpfur.
Folia Histochemica et Cytobiologica, 2008 The Gomori-positive glia are periventricular astrocytes with abundant cytoplasmic granular material, predominantly occupying a periventricular site in the brain.
Marta Góralska +3 more
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Thiosulfoxide (Sulfane) Sulfur: New Chemistry and New Regulatory Roles in Biology [PDF]
Molecules, 2014 The understanding of sulfur bonding is undergoing change. Old theories on hypervalency of sulfur and the nature of the chalcogen-chalcogen bond are now questioned. At the same time, there is a rapidly expanding literature on the effects of sulfur in regulating biological systems.
, Cooper Arthur J L, John I Toohey
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Sulfane Sulfur in Toxicology: A Novel Defense System Against Electrophilic Stress
Toxicological Sciences, 2019 Electrophiles can undergo covalent modification of cellular proteins associated with its dysfunction, thereby exerting toxicity. Small nucleophilic molecules such as glutathione protect cells from electrophilic insult by binding covalently to electrophiles to form adducts that are excreted into the extracellular space.
Yoshito Kumagai, Kumagai Yoshito
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2H-Thiopyran-2-thione sulfine, a compound for converting H2S to HSOH/H2S2 and increasing intracellular sulfane sulfur levels [PDF]
Nature CommunicationsReactive sulfane sulfur species such as persulfides (RSSH) and H2S2 are important redox regulators and closely linked to H2S signaling. However, the study of these species is still challenging due to their instability, high reactivity, and the lack of ...
Qi Cui +16 more
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