A sulfide-sensor and a sulfane sulfur-sensor collectively regulate sulfur-oxidation for feather degradation by Bacillus licheniformis [PDF]
Communications Biology, 2023 The feather-degrading bacterium Bacillus licheniformis MW3 contains a sulfur-metabolizing gene cluster, in which one sulfide-sensor and one sulfane sulfur-sensor synergistically control gene expression, enabling the bacterium to grow on bird feathers.
Chao Tang +7 more
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The glial Gomori-positive material is sulfane sulpfur. [PDF]
Folia Histochemica et Cytobiologica, 2008 The Gomori-positive glia are periventricular astrocytes with abundant cytoplasmic granular material, predominantly occupying a periventricular site in the brain.
Marta Góralska +3 more
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Metabolic Reprogramming of Sulfur in Hepatocellular Carcinoma and Sulfane Sulfur-Triggered Anti-Cancer Strategy [PDF]
Frontiers in Pharmacology, 2020 Metabolic reprogramming is a cancer hallmark. Although the reprogramming of central carbon has been well documented, the role of sulfur metabolism has been largely overlooked.
Ximing Zhang +7 more
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Targeting hepatic sulfane sulfur/hydrogen sulfide signaling pathway with α-lipoic acid to prevent diabetes-induced liver injury via upregulating hepatic CSE/3-MST expression [PDF]
Diabetology & Metabolic Syndrome, 2022 Background Diabetes-induced liver injury is a complication of diabetes mellitus of which there are no approved drugs for effective treatment or prevention.
George J. Dugbartey +6 more
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Using resonance synchronous spectroscopy to characterize the reactivity and electrophilicity of biologically relevant sulfane sulfur [PDF]
Redox Biology, 2019 Sulfane sulfur is common inside cells, playing both regulatory and antioxidant roles. However, there are unresolved issues about its chemistry and biochemistry.
Huanjie Li +10 more
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Redox Biology, 2022 Fluorescent probes are useful tools for the detection of sulfane sulfurs in biological systems. In this work, we report the development of SSP4, a widely used probe generated in our laboratory.
Moua Yang, Robert Flaumenhaft, Shi Xu
exaly +3 more sources
2H-Thiopyran-2-thione sulfine, a compound for converting H2S to HSOH/H2S2 and increasing intracellular sulfane sulfur levels [PDF]
Nature CommunicationsReactive sulfane sulfur species such as persulfides (RSSH) and H2S2 are important redox regulators and closely linked to H2S signaling. However, the study of these species is still challenging due to their instability, high reactivity, and the lack of ...
Qi Cui +16 more
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Mitochondrial dysfunction-driven AMPK-p53 axis activation underpins the anti-hepatocellular carcinoma effects of sulfane sulfur [PDF]
Scientific ReportsHepatocellular carcinoma (HCC) is the most prevalent form of primary liver cancer, notoriously refractory to conventional chemotherapy. Historically, sulfane sulfur-based compounds have been explored for the treatment of HCC, but their efficacy has been ...
Xue Zheng +14 more
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Intermediates in the Sox sulfur oxidation pathway are bound to a sulfane conjugate of the carrier protein SoxYZ. [PDF]
PLoS ONE, 2017 The Sox pathway found in many sulfur bacteria oxidizes thiosulfate to sulfate. Pathway intermediates are covalently bound to a cysteine residue in the carrier protein SoxYZ.
Daniel B Grabarczyk, Ben C Berks
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Acceleration of Anaerobic Cysteine Transformations to Sulfane Sulfur Consequent to γ-Glutamyl Transpeptidase Inhibition [PDF]
The Scientific World Journal, 2012 Toxicity of drugs and radiation in the cells is largely dependent on the level of thiols. In the present studies, an attempt has been made to inhibit γ-glutamyl transpeptidase (γGT) activity in EAT-bearing animals tissue.
Inga Kwiecień +2 more
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